Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Mitotic slippage"”.
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Mitotic slippage by ATP depletion and its mechanism
… the existence of energy checkpoint during mitotic progression. In our hand, ATP depletion by the co-treatment with 2-deoxy glucose (2-DG) and sodium azide (NaN3) during interphase caused robust cell cycle arrest, supporting the existence of energy checkpoints sensing shortage of ATP supply …
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Targeting c-met in sonic hedgehog medulloblastomas
… to TP53wt cells, where it showed primarily mitotic delay. We observed a complex and diverse pharmacological response to c-MET inhibitors; while tivantinib strongly induce mitotic cell death, through downregulation of MCL-1 protein, foretinib and crizotinib causes mitotic slippage, phenomenon …
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Investigating the origins of polyploidy in Barretts oesophagus and oesophageal adenocarcinoma
… of dividing OEAC cells present with an abnormal mitotic phenotype, the most prevalent being a defect in chromosome congression and alignment. Whole genome and RNA sequence analyses of OEAC cell lines indicated numerous copy number changes and gene expression alterations of important inner and …