Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Mitogen-Activated Protein Kinase 1"”.
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Nuclear Behaviors of ERK1/2 Signaling
… (Ras)- rapidly accelerated fibrosarcoma (Raf)- mitogen-activated protein kinase/extracellular signal-regulated protein kinase (MAPK/ERK) kinase (MEK)- ERK pathway is essential for proper development and homeostatic regulation in eukaryotic cells. Many pathway functions are carried out by ERK1 …
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Investigation of the cAMP-mediated inhibitory mechanism on the signalling pathways of 2 cytokines: IL-6 and leptin in endothelial cells
… in HUVECs. Further investigation of this SOCS protein in the context of IL-6 and leptin signalling in endothelial cells would be of interest in terms of possibly elucidating the molecular mechanisms underlying the protective effects of cAMP. Results from this study demonstrated a cAMP-mediated …
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Nucleocytoplasmic Localization of MAPKs
Mitogen-activated protein kinases (MAPKs) comprise a family of protein-serine/threonine kinases, which participate in signal transduction pathways that control intracellular events. MAPKs are regulated by phosphorylation cascades, which are usually initiated by external stimuli including a variety …
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Identification and Characterization of the Multifunctional Epigenetic Regulator CFP1 as an ERK1/2 Substrate
… covalent modifications to both histone proteins and DNA, the presence of transcription factors, and modification directly to the transcriptional machinery. Our lab is interested in the control of cellular processes by the mitogen activated protein kinases ERK1/2. In a yeast two-hybrid …
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Identification of a Novel ERK 1/2-Interacting A-Kinase Anchoring Protein
… identified in Chlamydomonas, radial spoke protein 3 (RSP3) is one of at least twenty identified radial spoke structural components of motile cilia and is required for axonemal sliding and flagellar motility. The mammalian orthologs for this and other radial spoke proteins, however, remain …