Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"Mitogen Activated Kinase"”.
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The function of Drosophila Integrin-Dim7-Elmo-Mbc→Rac signaling pathway in the muscle attachment formation and maintenance
… tendon cell differentiation factors Stripe or activated Mitogen-activated kinase (pMAPK) are missing from the tendon cells. Our data shows that Msk signals from the muscle cell via the secreted Epidermal growth factor receptor (Egfr) ligand Vein to regulate tendon cell maturation. In the …
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Molecular mechanisms controlling complex traits in yeast
… strain requires the filamentation mitogen activated kinase pathway (fMAPK) for agar adhesion but the S288c strain does not. I found that S288c is able to bypass the fMAPK pathway because it contains an allele of the transcription factor RPI1 that promotes transcription of the gene …
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p38 MAPK Signalling in Endothelial Apoptosis
… main objective was to elucidate the role of p38 mitogen activated kinase (p38) in such systems, using the endothelial cell line EA.hy926. We found that p38 plays an important proapoptotic role in both, TNF- and doxorubicin-induced apoptosis. In TNF-induced cell death, p38 mediates phosphorylation …
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Notch Signaling Is Important in the Survival, Proliferation, and Self-Renewal of the Putative Breast Cancer Stem Cell Population
… a RT-qPCR based approach as well as several kinase inhibitors including those that inhibit c-Jun N-terminal kinase and the p38 mitogen activated kinase.</p><p>The CSCs possessed elevated levels of Notch activation compared to the non-CSCs regardless of breast cancer phenotype, sample origin …
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Early Effects of Organophosphate Compounds on In Vitro Intracellular Signaling and Levels of Active Neurotrophin Receptors, and on In Vivo Neurotrophin Concentrations
… digital morphometry. These studies revealed that activated forms of high-affinity and low-affinity neurotrophin receptors are present after OP compound exposure, that the ratio of these two receptors to each other is stable after OP compound exposure, and that the activated form of the …
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Characterization of insulin-stimulated protein kinase cascade in normal and diabetic rats and the effects of vanadium
Multiple protein kinases acting in a sequential manner have been identified to constitute a kinase cascade that mediates growth factor or mitogen-activated signal transduction. The cascade is triggered at the cell membrane by the activation of receptor tyrosine kinases, which pass on the signal in …
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Mechanisms of selective translational control under short-term high light stress
… include i.a. energy signaling pathways employing MITOGEN-ACTIVATED KINASE (MPK) and signaling via altered ratios of reduced (GSH) to oxidized forms (GSSG) of the low molecular weight antioxidant glutathione. Analyses of polysome-association of STRESS-ASSOCIATED PROTEIN (SAP) 2 and 3, both actively …