Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Mitochondrial changes"”.
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Age-Related Hamster Mitochondrial Changes and Oocyte Changes Following Autologous Platelet Mitochondrial Microinjection
… study's objective was to verify age-related mitochondrial changes in oocytes from old hamsters compared with those from young hamsters. We used autologous platelet mitochondrial microinjection to improve the mitochondrial quality and quantity of aged oocytes to improve their pregnancy …
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Using gravity to help us understand the AMPK-PGC-1α axis in skeletal muscle from healthy young males
… be involved in regulating these exercise-induced mitochondrial changes is called peroxisome proliferator-activated gamma coactivator 1-alpha (PGC-1α). Generally, the harder someone exercises (i.e. higher exercise intensities), the more PGC-1α increases. There are also several proteins that ‘turn …
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An Analysis of Mitochondrial DNA in Rett Syndrome and Other Neurodegenerative Disorders
<p>Mitochondrial dysfunction resulting from mutations on mitochondrial DNA (mtDNA) is being recognized in a growing spectrum of diseases. These diseases, resulting from single base mutations, large deletions, or insertions, have been largely neuromuscular in origin. However, as an understanding of …
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NEW INSIGHTS INTO THE REGULATION OF MITOCHONDRIAL OUTER MEMBRANE PERMEABILIZATION DURING APOPTOSIS
… addition, Apaf-1 is a critical component of the mitochondrial pathway and is generally thought to reside downstream of MOMP. My dissertation investigates the molecular requirements essential for MOMP during stress-induced and receptor-mediated apoptosis. Distinct clones of Jurkat T-lymphocytes …
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Exercise tolerance and skeletal muscle structure and function in patients with severe chronic heart failure
… Significant histological and ultrastructural changes were found in all SM biopsies from patients with CHF. These included atrophy and hypertrophy of fibres, fibre splitting, internalized nuclei, nuclear knots, moth-eaten fibres, increased lipid droplets. Electron microscopy showed a large …