Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"Mitochondria defects"”.
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Modeling Complex Neurological Disorders With Human Induced Pluripotent Stem Cells
… encode for proteins that directly localize to mitochondria, we tested the hypothesis that SZ and 22qDS are associated with mitochondria defects. We found that HiPSC-derived neurons from 22qDS+SZ indeed have mitochondria deficits. We further discovered that haploinsufficiency of only the 22qDS …
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Neuronal and Mitochondrial Protection in Chronic Parkinsonism
… Parkinson’s disease (PD), oxidative stress and mitochondrial damage have emerged as one of the attractive biochemical mechanisms. However, most of the past studies linking mitochondrial dysfunction to neuronal degeneration have been carried out in vitro or in acute in vivo studies. It is not …