Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Mitochondria biogenesis"”.
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Targeting The Redox System to Overcome Mechanisms of Drug Resistance In Chronic Lymphocytic Leukemia
… protein regulates multiple functions including: mitochondria biogenesis, response to DNA damage and redox balance. The objectives of the study were to determine the status of mitochondria in the mouse TCL1/p53<sup>-/-</sup> CLL model, role of the enhancer of zeste homolog 2 (EZH2) in drug …
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The Role of Amp-Activated Protein Kinase (Ampk) In Tumorigenesis
… of AMPK in cancer, such as autophagy and mitochondria biogenesis. However, how AMPK promotes cancer progression is still not clear. Here, we show that AMPK is essential for EGF-induced Akt activation, Glut1 expression, and glucose uptake. AMPK is also required for various stresses induced …
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SHORT-CHAIN FATTY ACIDS INDUCED AUTOPHAGY SERVES AS AN ADAPTIVE STRATEGY FOR RETARDING MITOCHONDRIA-MEDIATED APOPTOTIC CELL DEATH
… overproduction of reactive oxygen species due to mitochondrial dysfunction involving the induction of MPT and loss of Δψ. In this context, mitochondria biogenesis was initiated to recover cellular energy homeostasis. Importantly, when autophagy was prevented either pharmacologically ii (3-MA or …
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The Effect of Mitochondrial Dynamics on Cell Cycle Progression
… been barely studied. Here, we investigated how mitochondria duplicate and partition during cell cycle progression. Using cell synchronization techniques, different phases of cells in cell cycle were collected and analyzed for the changes in mitochondrial DNA copy number and mitochondrial mass. …