Global ETD Search
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Showing 1 to 6 of 6 for “"Mitochondria, Muscle"”.
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Burn Serum Stimulates Mitochondrial Fission in C2C12 Myoblasts
BACKGROUND: Burn patients suffer muscle mass loss associated with a hypercatabolic status. Impairment of mitochondrial function has been observed in the muscle of burn patient's. OBJECTIVE: We hypothesize that muscle atrophy due to burn injur y is associated with an alteration in mitochondrial …
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Investigation into Tissue-Specific Mechanisms of Mitochondrial Dysfunction: Models of SUCLA2 Deficiency and a Screen for Potential Genetic Modifiers
With no currently effective treatments available, mitochondrial diseases are one of the most common forms of inherited multisystem disease. Primary disorders of the mitochondria affect an estimated 1 in 4,300 people with typical onset in early childhood. Mitochondrial disorders are classically …
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Sex Differences in Cancer Cachexia and a Novel Mitochondrial Target for Cancer-Induced Muscle Wasting
… by marked weight loss including skeletal muscle atrophy that affects approximately 80% of cancer patients. Current therapeutic treatments including pharmacological and nutritional intervention are insufficient to prevent or reverse it. Prior studies demonstrated lower muscle mass, impaired …
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IMPACT OF DRP1 ACTIVATION, UNFOLDED PROTEIN RESPONSE INDUCTION AND FGF21 LEVELS IN DMD PROGRESSION
… dystrophy (DMD) is a severe genetic progressive muscle-wasting disease. The transmission of this pathology is X-linked recessive with an incidence of at least 1:5000 newborn boys. Patients typically present the first symptoms related to motor impairments very early in childhood and if not …
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The molecular memory of exercise in skeletal muscle
Skeletal muscle constitutes nearly half of our body weight and reduction of muscle mass is linked to increased risk of mortality and metabolic disorders. Further, skeletal muscle mass and function decline with age, a term known as sarcopenia. These reductions in muscle mass and function can be …
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The molecular memory of exercise in skeletal muscle
Skeletal muscle constitutes nearly half of our body weight and reduction of muscle mass is linked to increased risk of mortality and metabolic disorders. Further, skeletal muscle mass and function decline with age, a term known as sarcopenia. These reductions in muscle mass and function can be …