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Showing 1 to 4 of 4 for “"Minisci reaction"”.
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Development of Catalytic Enantioselective Minisci-type Reactions
… of a protocol for the catalytic enantioselective Minisci-type addition of prochiral radicals to heteroarenes through the dual techniques of chiral Brønsted acid catalysis and photocatalysis. The first research section details the initial hypothesis, design and implementation of our strategy for …
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Studies towards controlling selectivity in Minisci reactions
… heteroarenes, commonly referred to as Minisci-type reactions, comprises an important class of transformations for the direct functionalisation of heteroaromatic compounds. Recent advances in radical generation methods, particularly due to developments in photoredox catalysis, have …
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Selective functionalization of azines via phosphonium salts
… the pharmaceutical industry. The protocol of the reaction is simple, and it functions on a wide range of building blocks and complex molecules. Additionally, the tritiation protocol was effectively applied on a selection of drug molecules through a collaborative effort with Merck. In chapter 3, a …