Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Microwell Platform"”.
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The Influence of Human Umbilical Vein Endothelial Cells in the Formation of Glioblastoma Spheroids in Three-Dimensional Microwells
… GBM cells with endothelial cells in the hydrogel microwells would mimic the in vivo microenvironment of tumor cells. Thus, we could provide beneficial 3D in vitro co-culture models for GBM treatment with oncolytic adenovirus, Delta-24-RGD (Δ24RGD). Therefore, in the first part of this study, we …
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A noninvasive screening tool for cell fate determination using raman spectroscopy and machine learning in tissue engineering and microbiology applications
… success. Therefore, miniature biomaterial platforms for screening thousands of putative stimuli have been devised to identify the combinations of factors that drive self-renewal in vitro while reducing the numbers of rare HSCs required for screening. To correlate the extrinsic cues …
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Investigating the role of geometry, mechanics, and microenvironmental cues on liver progenitor cell differentiation
… describe the development of a hydrogel-based microwell platform, which I used to produce arrays of 3D, multicellular liver progenitor cell microtissues in constrained geometries. These generated distinct mechanical profiles which I modeled with finite element method software, which was …
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Microfluidic processes to create structured microparticle arrangements and their applications
… and development of a new microfluidic platform, porous microwell arrays, to create structured large-scale microparticle arrays using a scaling theory, which is a function of particles' characteristics. Lastly, we demonstrate the potential of generated particle arrays in various …