Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 43 for “"Microvessel"”.
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Development of fast ultrasound super-resolution microvessel imaging
Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2025-03-28 without embargo terms
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Deep learning for super-resolution ultrasound microvessel imaging
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2026-05-01
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Investigating Transluminal Endothelial Bridging in a Microvessel-on-a-Chip
Angiogenesis is the process of new blood vessel generation that is essential to form and sustain new tissue in development and disease. Intussusceptive angiogenesis (IA), whereby blood vessels split into two, is one of the two main mechanisms of angiogenesis yet it remains poorly understood more …
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A microvessel-on-a-chip for studying how tumor-derived factors prime the endothelium for extravasation
… vivo. This dissertation thus aimed to create a microvessel-on-a-chip model for studying extravasation and its underlying processes in vitro with physiological relevance and high spatiotemporal resolution not possible with traditional culture models. ☐ The first objective was developing the …
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Microvessel structure formation in a 3D perfused co-culture of rat hepatocytes and liver endothelial cells
… cells proliferated moderately and organized into microvessel-like structures as observed by in situ multi-photon microscopy. By mixing female endothelial cells with male hepatocytes, the female cell population increased from initially -7% on day 1 to -12% on day 13, as determined by quantitative …
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Correlation of Cyclooxygenase-2 and Microvessel Density with Prognosis in Transitional Cell Carcinoma of the Upper Urinary Tract
… study, the relationship of COX-2 expression and microvessel density (MVD), a reflection of angiogenesis, with prognosis in patients with transitional cell carcinoma of the upper urinary tract was investigated. MATERIALS AND METHODS: Formalin-fixed, paraffin-embedded tissue sections of …
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Impact of Caveolin-1 Expression and Microvessel Density on the Prognosis of Upper Urinary Tract Transitional Cell Carcinoma
… the relationship of caveolin-1 expression and microvessel density (MVD), a reflection of angiogenesis, with prognosis in patients with UUT-TCC. MATERIALS AND METHODS: Formalin-fixed, paraffin-embedded tissue sections of UUT-TCC from 98 patients who had undergone radical nephroureterectomy were …
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Microbubble localization using multivariate gaussian fitting for super-resolution ultrasound localization microscopy
… localization microscopy is an advanced microvessel imaging modality. Multiple studies have proved its significant preclinical and clinical application potential. As an important step of the super-resolution ultrasound localization microscopy, current microbubble localization methods need …
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Mathematical models for interendothelial cleft
… structural mechanisms in the regulation of microvessel permeability by cAMP. The other is to examine the charge effects of surface glycocalyx on microvessel permeability; To investigate the microstructural mechanisms of decreasing microvascular permeability induced by the enhancement of …
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Effect of Calcium Phosphate Ceramic Architectural Features on the Self-Assembly of Microvessels In Vitro
… of microns, can be used to direct the growth of microvessels into the core of scaffolds. A pipeline was developed for the production of hydroxyapatite surfaces with controlled architecture. Three batches of hydroxyapatite were used with two different particle morphologies and size distributions. …
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Mathematical modelling of transport across blood vessel walls
… degenerative diseases is filtration across microvessel walls. The role of the microvessel wall is to let oxygen and nutrients contained in the blood stream to reach the interstitium, and ultimately the surrounding cells, while blocking macromolecules. An understanding of these processes is …
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Cancer Associated Fibroblast Derived Angiogenic Factor Mfap5 In Ovarian Cancer Progression
… between stromal MFAP5 expression and intratumor microvessel density, suggested a pro-angiogenic role of MFAP5. This study aims at delineating the functional roles and mechanisms by which stromal MFAP5 modulates ovarian tumor progression and angiogenesis and investigating the potential of …
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Μελέτη της κλινικής σημασίας της αγγειογένεσης σε ασθενείς με νόσο hodgkin
… evaluate various morphometric characteristics of microvessels, highlighted by means of anti-CD34 immunohistochemistry, in the lymph node of 286 patients with HL at diagnosis and investigate their relationship with several clinicopathologic parameters and prognosis. EXPERIMENTAL DESIGN: …
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A Tissue-Engineered Microvascular System to Evaluate Vascular Progenitor Cells for Angiogenic Therapies
… cues necessary to support physiological microvessel formation in vitro; (2) poly(ethylene glycol) (PEG) hydrogel systems can support 3D microvessel formation by hCB-EPCs in coculture with mural cells; (3) mesenchymal cells, derived from either umbilical cord blood (MPCs) or bone marrow …
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Imaging biological water permeability barriers using CARS microscopy
… samples poses many significant challenges. Microvessel microfluidic systems have the possibility to facilitate microscopy studies of vascular barrier function due to their flexibility of design, relative ease of preparation, and relative simplicity. In this thesis, the fabrication process of …
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Microviscometric Analysis of Microvascular Hemodynamics in Vivo
… rheological properties of blood flow in intact microvessels in vivo. A new microviscometric approach is presented, which we have validated through glass-tube studies in vitro (30--80 mum in diameter) and through isovolemic hemodilution studies in vivo, that provides estimates of hemorheological …
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Paxillin-dependent control of tumor angiogenesis
… the mechanism by which it contributes to normal microvessel network formation and tumor angiogenesis. I found that paxillin knockdown increases microvessel density but causes loss of sprout orientation. These characteristics resemble those of tumor vasculature, and, in fact, studies revealed that …
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The Effect of Red Blood Cell Velocity on Oxygenation Measurements using Resonance Raman Spectroscopy
… to acquire variables such as red cell velocity, microvessel diameter and hemoglobin oxygen saturation at multiple sites in selected microvascular networks. Using this system, resonance Raman spectroscopy was employed to measure hemoglobin oxygen saturation gradients in arterioles and venules of …
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The Influence of Structure and Surface Biochemistry on Cell Function and Angiogenesis in Collagen Scaffolds
… surface chemistry properties on the formation of microvessels. Firstly, the influence of mould design on architectural features of collagen scaffolds fabricated using lyophilisation was assessed using micro-computed tomography (Micro-CT) and scanning electron microscopy (SEM). A range of mould …
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