Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 4 of 4 for “"Microspikes"”.
-
Reexamining actin polymerization in maintaining cadherin mediated cell-cell adhesion
… In Chapter 2, I show that filopodium-like actin microspikes protrude perpendicularly at the apical junction to deliver cadherins to where cadherins are missing on the neighboring cell, functioning as a repair mechanism for small defects in the otherwise continuous cadherin belt; myosin II …
-
Frazzled And Abelson Interact To Regulate The Actin Cytoskeleton In Drosophila
… processes underlying formation of filopodia, microspikes and membrane ruffles. So, we established a Drosophila S2 cell culture paradigm to study how Frazzled and Abelson may co-regulate actin-dependent morphology. Ectopic expression of Frazzled in S2 cells produces long filopodia-like …
-
Novel approaches to engineer glucose biosensors
… design of coil-type implantable biosensors. Microspikes, which are able to painlessly penetrate the skin layer, were fabricated using lithographic techniques and sputtered with gold to serve as an electrode. The biosensor design is based on thiomalic acid self-assembled monolayer (SAM) on …
-
Reconstitution Of Rho Gtpase Interactions At The Membrane
… cytoskeletal architecture and induce filopodia/microspikes, it is essential for the ability of an oncogenic mutant of Cdc42 to transform fibroblasts. Thus, these findings highlight the importance of Cdc42 being localized to a PIP2-enriched membrane site to engage those signaling partners that …