Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 58 for “"Microscopy Imaging"”.
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U-Net Network Enhancements to Facilitate Rapid Electron Microscopy Imaging for Connectomics
Imaging the structural and functional connections between cells in the brain allows neuroscientists to understand the brain by studying neuronal wiring diagrams. To automatically segment and classify images that are used in the construction of these neuronal wiring diagrams, or connectomes today, …
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Mechanical behavior of ultrastructural biocomposites
… phase of biomacromolecules. High resolution microscopy imaging was employed to investigate the microscale features of seashell nacre to reveal the nucleation points within tablets, the sector boundaries and an overlap between tablets of neighboring layers of [approx.] 20 %. Aragonite, the …
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Image and video analysis techniques for cellular microscopy
… AUTHOR'S REQUEST.] Advances in automated digital microscopy imaging made it possible to produce multi-dimensional image data that can capture dynamic characteristics of sub-cellular and cellular structures. Biologists routinely produce large volumes of bioimage time lapse data that necessitates …
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Synthesis, Characterizations, And Evaluation Of New Reactive Two-photon Absorbing Dyes For Two-photon Excited Fluorescence Imaging Applications
… for the development and application of the novel imaging modality utilizing multiphoton absorption and its extraordinary contribution to recent advances in bioimaging. Intimately involved in the revolution of nonlinear bioimaging has been the development of optical probes for probing biological …
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Quantitative capacitance measurements using a scanning probe microscope
… force microscope with scanning capacitance microscopy (SCM) capability can be employed in a nontraditional fashion to quantitatively measure the capacitance of metal-oxide-semiconductor (MOS) structures. The capability to deduce sample capacitances is based on resonant frequency shifting, …
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Representation Learning Associates Patients’ Risks for Metabolic Diseases with Features of Their Lipocytes
… we make use of a recent large-scale lipocyte microscopy imaging dataset. By learning a representation of multi-channel lipocyte microscopy images using a convolutional autoencoder, we perform unsupervised clustering on the learnt representations to identify different cell states. We analyze …
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Nonlinear interferometric vibrational imaging for applications in the study and diagnosis of breast cancer
… thesis deals with the problem of developing a microscopy imaging technique with fast acquisition rates and label-free chemical selectivity for the study of tumor formation and its diagnosis in early stages of development. Spontaneous Raman scattering microscopy studies on human breast …
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Characterization and modeling of cell activation upon TGF-β1 stimulation in a 3-D culture system
… immunofluorescence staining (IF) and confocal microscopy imaging of α-SMA in each cell embedded layer. Our results revealed the spatial-temporal profiles of the conversion from normal fibroblasts to myofibroblasts in 3-D culture upon TGF-β1stimulation. The conversion starting time, speed and …
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Femtosecond CARS Microscopy to characterize lipid droplets in Engineered Adipose Tissue
… microscopic techniques, such as fluorescence microscopy, provides excellent selectivity of lipid-based structures inside adipose tissue cellular structures based on staining with compound dyes. However, fluorescence staining limits multiplex imaging, and requires time consuming steps in …
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Multiscale chemomechanics of polymer deformation under contact : predicting structure-property correlations from the bulk to the interphase
… combination of nanoindentation and atomic force microscopy imaging. In addition, the classic, time-dependent metric creep compliance J(t) is used to establish the experimental conditions necessary for linear elastic behavior for a set of thermoplastic and thermoset materials. For large …
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Direct imaging of self-assembly behaviors of colloids: from the microscale plates to the nanoscale cubes
… anisometric colloids and developing direct imaging tool of liquid-phase transmission electron microscopy (TEM) to visualize and quantify the less-explored nanoparticle self-assembly dynamics in solution. I begin by engineering highly directional interactions of micron-sized silver plates …
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Nuclear magnetic resonance microscopy and diffusion
… in vivo with a home-built high resolution microscopy imaging probe. It is one of the most stable microimaging system designed and fully equipped for microscopic fMRI study. This work is an advancement of using MRI to study fundamental neuron science and cell signal pathways in vivo. NMR …
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Nanoscale Morphology and Electrical Behaviour of a Pressure Sensitive Ink
… resolution scanning and transmission electron microscopy, focused ion beam and EDX elemental analysis in conjunction with DC electrical characterization. The research has aimed to investigate possible links between the structure and electrical behaviour of the inks. The results have shown that …
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Nickel and cobalt sulfide nanomaterials for magnetic and energy applications
… identified mainly by the x transmission electron microscopy imaging technique. Furthermore, it was discovered that docecylamine and hexadecylamine capping agents produced phase pure Ni3S4 and Ni3S2, respectively; phase identification was conducted using the powder X-ray diffraction technique. On …
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Advancing Dynamic Imaging for Microfluidic Stimulated Tissues: Biology, Techniques, and Applications
Using quantitative fluorescence microscopy imaging of cellular activities in intact tissues stimulated in a microfluidic device creates opportunities for studying major diseases such as diabetes and cancer. Despite a number of documented phenotypic traits of these diseases, the underlying …
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Deep learning for automatic microscopy image analysis
<p>Microscopy imaging techniques allow for the creation of detailed images of cells (or nuclei) and have been widely employed for cell studies in biological research and disease diagnosis in clinic practices.Microscopy image analysis (MIA), with tasks of cell detection, cell classification, and …
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Integration of Nano CT and SEM in the Characterization of Marcellus Shale
… shale rock sample by the combination of Nano CT imaging and Scanning Electron Microscopy imaging methodologies. The key components involve the uses of an appropriate sample preparation technique and application of complex imaging algorithm in digitising the shale sample and 3dimension image …
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Studies of G-Protein Coupled Receptors Incorporated Into a Novel, Nanoscale, Membrane-Mimetic System
… and imaged the rhodopsin-NABBs using electron microscopy (EM) to measure stoichiometry and receptor orientation. Using a combination of EM imaging and biochemical analyses, we correlated stability and signaling efficiency of rhodopsin in NABBs with either one or two receptors. We discovered …
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Unravelling the relationship between cigarette smoking and language development
… and Forster's resonance energy transfer (FRET) microscopy imaging. Our systematic review reported negative effects of prenatal CS exposure on offspring language outcomes in 13 of 14 studies reviewed. Our apFRET experiments found the RIC3 variants studied introduced did not affect the interaction …
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Investigating the movement of intestinal intraepithelial lymphocytes using an organoid co-culture system
… and by performing bright field and confocal microscopy imaging of the co-culture, I was able to visualize IEL movements. Indeed, IELs were observed to be highly motile inside organoids similar to previous studies. IL-15, a chemokine which is known to promote IEL proliferation and survival, …
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