Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 36 for “"Microring Resonators"”.
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Particle-enhanced biomolecule detection using silicon photonic microring resonators
… a detection platform based on silicon photonic microring resonators which is capable of making sensitive measurements of proteins, as well as other biomolecules, in complex matrices. The following chapters present the work I have completed towards the development of particle-based detection …
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Semi-analytic simulations of microring resonators with scattering elements
… and numerical simulation results of a microring resonator with a scattering element inserted. The spectral reflection of the scattering element can be engineered to realize wavelength-selective reflection for the integrated microring. In particular, a Fabry-Perot element can be used to …
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Surface modification of silicon photonic microring resonators for chemical sensing
Silicon photonic microring resonators have emerged as a promising technology for the sensitive detection of biological macromolecules, including proteins and nucleic acids. These bulk property detectors rely on the changes in the effective refractive index of the sensing region, eliminating the …
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Selective mode coupling in microring resonators for single mode semiconductor lasers
… based on the coupling of degenerate modes of a microring resonator, and investigation of the possibility of using them for improving the performance of laser diodes. In particular, we demonstrate a new type of compact, narrowband, on-chip reflector realized by selectively coupling degenerate …
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Silicon photonic microring resonators for the development of cancer protein biomarker assays
… presents the development of silicon photonic microring resonator technology in the Ryan Bailey research laboratory towards multiplexed cancer protein biomarker measurements. Microring resonator sensing technology relies upon changes in refractive index that induce a resonance shift in circular …
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Multiplexed protein biomarker analysis on silicon photonic microring resonators: translation towards clinical diagnostics
… on a platform based on silicon photonic microring resonator technology. This sensing technology has high potential for clinical diagnostics utility, as sensor chips of this platform can be cheaply manufactured through a highly scalable process. Moreover, continuous improvements in sensor …
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Advances in molecular-based diagnostics and biomolecular interaction screening using silicon photonic microring resonators
… meaningful predictive power. Silicon photonic microring resonators are a promising class of sensor well suited to biomarker quantitation due to their sensitivity, scalability and flexibility, enabling quantitative multiplexed analysis. Their sensing modality arises from interactions between …
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Expanding the toolbox for precision medicine with silicon photonic microring resonators and microfluidic technologies
… diagnostics. Most of the following work uses microring resonator arrays as the detection platform, a versatile silicon photonic biosensing technology. Chapter 1 reviews the applications of optical resonators in analytical chemistry. Microring resonators arrays are a class of whispering gallery …
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Multiplexed immunoassay development for precision medicine diagnostics and protein characterization using silicon photonic microring resonators
… multiplexed immunoassays with silicon photonic microring resonator arrays. Using this basic protocol for assay development, Chapters 3 and 4 describe two distinct approaches toward diagnosing and monitoring infectious disease related states. Chapter 3 focuses on designing a functional diagnostic …
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Multiplex analysis of protein-lipid and protein-membrane protein interactions utilizing silicon photonic microring resonators
… nanodiscs were integrated with silicon photonic microring resonators. Nanodiscs are easy to assemble, nanometer scale lipid bilayer discs which offer a high degree of control over lipid and membrane composition. Each nanodisc is held together by two membrane scaffold proteins that can be used as …
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Improving multiplexed RNA detection assays by interfacing enzymatic amplification strategies with silicon photonic microring resonators
… enzymatic processing steps with silicon photonic microring resonators, a technology pioneered by the Bailey Research Laboratory. While other efforts in lab have been geared to other classes of biomolecules, the developed assays discussed in this dissertation are designed to profile nucleic acid …
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The development of new sensing methodologies for nucleic acids using arrays of silicon photonic microring resonators
… platform based on arrays of silicon photonic microring resonators that is highly amenable for the quantitative, multiplexed detection of nucleic acids, in particular, miRNAs. We begin by demonstrating a label-free method for the quantitative, multiplexed detection of miRNAs. We further extend …
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Design, fabrication, and characterization of lithium niobate whispering-gallery-mode microdisk and microring resonators and grating couplers
… large bandwidth for modulation. Photonic microresonators developed in LiNbO3 thin-films serve as the basic design unit of such platforms. This thesis provides preliminary characterizations of LiNbO3 whispering-gallery-mode microring and microdisk resonators, a single-ring filter, and grating …
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Application of silicon photonic microring resonators to the study of surface bioconjugation and protein capture agent binding kinetics
… some of these issues, we employ silicon photonic microring resonators, an emerging surface-sensitive analysis method that our group has recently utilized for monitoring biomolecular binding and detection in an array-based, label-free biosensor format. First, aniline-catalyzed hydrazone ligation …
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Thermal detection in the long wave infrared and very long wave infrared regions
… applications. The advancement of microphotonic resonators has brought interest of their use as detection devices due to their small size and high quality factors. Implementing silicon photonic microring resonators as a means of a thermal detector gives rise to higher speed and detectivity, as …
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Vertical waveguide-coupled microring resonator: Design and simulation
… in calculating the coupling in micron-scale microring resonators. This method has been shown to give fast and accurate results in calculating the properties of in-plane coupling structures. We have adapted this algorithm to analyze the properties of a vertical coupling structure in detail. …
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Optimization of tunable silicon compatible microring filters
Microring resonators can be used as pass-band filters for wavelength division demultiplexing in electronic-photonic integrated circuits for applications such as analog-to-digital converters (ADCs). For high quality signal transmission, the resonant frequency of the filter has to be held at certain …
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Enhancing the performance of silicon photonic biosensors for clinical applications
… electric (TE) and transverse magnetic (TM) mode resonators in various waveguide topologies. Specifically, TM mode microring resonators, microdisk resonators, thin waveguide resonators, and sub-wavelength grating microring resonators that provide an order of magnitude sensitivity improvement over …
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Refractometry Studies of the Optical Properties of Polymer Films and the Development of Polymer Coated Refractive Index Sensors
… sensors, such as silicon-on-insulator (SOI) microring resonators are one possible platform, but require coatings selective to the analytes of interest. A homemade prism refractometer is reported and used to characterize the interactions between polymer films and liquid or vapour-phase …
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