Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 28 for “"Microrheology"”.
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X -Ray Diffraction Rotational Microrheology
Rotational single particle tracking microrheology can be used to find the storage and dissipative behavior of viscoelastic fluids of much higher viscosity than translational single particle tracking. The technique of X-ray diffraction rotational tracking has the ability to track the rotational …
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Microrheology and microstructure of poly(vinyl alcohol)-based physical gels
We study the microrheology and microstructure of physically cross-linked poly(vinyl alcohol) (PVA) gels using atomic force microscopy, dynamic light scattering and particle tracking. We compare the microscopic rheological properties with the bulk properties measured using conventional shear …
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Fluorescence laser tracking microrheology for quantitative studies of cytoskeletal mechanotransduction
… instrument for fast fluorescence laser tracking microrheology (FLTM). This novel method aims at experimentally deriving cellular viscoelastic properties from the passive monitoring of fluorescent microspheres undergoing Brownian motion inside the tested sample. Further instrument enhancement even …
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Mechanics and dynamics of living mammalian cytoplasm
Passive microrheology, a method of calculating the frequency dependent complex moduli of a viscoelastic material has been widely accepted for systems at thermal equilibrium. However, cytoplasm of a living cell operates far from equilibrium and thus, the applicability of passive microrheology in …
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Integrating novel rheological tools with microscopy to characterize viscoelastic properties of complex materials
… of the available techniques in the field of microrheology and interfacial rheology and overcome them using the novel rheological techniques that we have developed. Passive particle tracking microrheology (PTM) is a technique that uses Brownian motion of colloidal probe particles to …
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Microfluidics enhanced synthesis of micellar nanostructures
… FISPs are obtained by using one point passive microrheology and two point passive microrheology. The rheological properties variation from the original micellar solutions to their corresponding FISPs is associated with the structural evolution from the precursor to FISPs. The formation of FISPs …
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Bulk and micro-scale rheology of an aging, yield stress fluid, with application to magneto-responsive systems
… molecular scales. The developing sub-field of microrheology, which explicitly examines flow and deformation behavior on microscopic length scales, provides additional clarity to this connection between rheology and microstructure. Aging materials, whose rheological properties evolve over time, …
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Multiple particle tracking to assess the microstructure of biological fluids
… of the system. This probing technique, called microrheology, has received much interest in the last few decades due to the importance of a materials local properties in its function and its macro-scale characteristics. These new assessments are especially relevant in soft matter sciences such …
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Modeling the Motion of Solid Objects Immersed in Viscoelastic Fluids
… the potential to improve the ways in which microrheology measurements are made and interpreted. This thesis aims to develop a flexible, adaptable framework for describing the motion of geometrically simple objects in weakly elastic fluids by adapting well-established and robust analytical …
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Elucidating bioadhesive processes in nasal drug delivery systems
… mucin were analysed using standard rheology and microrheology. Greater synergy was found with high molecular weight, linear, ionic polymers; factors which allow for improved chain interactions. Texture analysis of the formulations confirmed that the adhesive forces increased for higher molecular …
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DNA-colloid systems and micro-rheology
… the practicalities and limitations of passive microrheology in gaining access to valid rheological information. In Chapter 2, we present a newly developed realtime monitoring algorithm for complex moduli in optical tweezer micro-rheology sys,tems. Further to eliminating high frequency …
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Broadband Rheological Characterisation of Soft Functional Materials
… and has led to a significant rise in the use of microrheology, where tracer particles provide indirect information about the viscoelasticity of the fluid, in which they are embedded. Recent advances in the fields of optics and electronics paved the way for using laser trapping and light …
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Suspension, yielding, microstructure and applications of bacterial cellulose dispersion
… bacterial cellulose fiber networks using a new microrheology technique developed specifically for this purpose. The fiber gels exhibit a dynamic structural rearrangement response to applied stress that is shown to be advantageous in applications like particle suspension and surface coating. The …
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Intruder Dynamic Response in Particulate Media
… future studies in the area. We find the `microrheology' of the intruder can be traced back to the properties of underlying, original, unperturbed packing, thereby providing a method to characterize the mechanical properties of the material that may otherwise be unavailable. To perform this …
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Linear and Non-Linear Mechanical Nature of a Living Mammalian Cytoplasm
… of the thesis, we develop high-frequency passive microrheology, a high-throughput, non-invasive, and inexpensive method to measure the frequency dependent complex moduli of the cytoplasm using the fluctuations of tracer particles. We use a combination of theoretical and experimental analysis to …
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Near-Field Hydrodynamics of Optically Trapped Colloids in Simple and Complex Fluids
… on temperature- and concentration-dependent microrheology. The viscoelasticity behaviour is quantitatively analysed using complex G modulus, where we observe F127’s resemblance of a Maxwellian fluid. A theoretically expected re-entrant liquid behaviour is present in our measurement, owing to …
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Studying the Role of Mechanical Properties of Cancer Cells in Tumour Detachment, Migration and Secondary Tumour Formation
… intracellular stiffness, particle tracking microrheology was used in 2D and 3D contexts. Protein content of actin and tubulin was quantified with Western blotting and the oncogenic factor TBX3 was assessed with immunofluorescence techniques. The results show that melanoma progression led to …
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Correlation Force Spectroscopy for Single Molecule Measurements
… and have used it in two applications (1) microrheology of Newtonian fluids and (2) single molecule force spectroscopy. To understand the correlation in thermal fluctuations of two cantilevers I initially validated the theoretical approach for analyzing correlation in terms of deterministic …
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Cancer Cell Mechanics in Chemoresistance and Chemotherapeutic Drug Exposure
… a combination of Multiple particle tracking microrheology (MPTM), quantitative RT-PCR and Western blotting techniques were utilised to demonstrate changes in cytoskeletal elements that are responsible for cellular mechanics. MPTM was developed as an approach to map intracellular mechanical …
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