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Batch and continuous production of stable dense suspensions of drug nanoparticles in a wet stirred media mill

Afolabi, Afolawemi

One way to improve the bioavailability of poorly water-soluble drugs is to reduce particle size of drug crystals down to nanoscale via wet stirred media milling. An increase in total surface area per mass loading of the drug and specific surface area as well as reduced external mass transfer …

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