Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 263 for “"Microfluidic devices"”.
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Droplet behaviour in microfluidic devices
… a study to understand the various aspects of a microfluidic device. In the first half we take the role of an end user, experimenting to learn how best to use the device efficiently. In the second half we are the manufacturer, trying to fabricate a user friendly, and fully functioning …
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Microfluidic Devices for Bioanalytical Applications
Poly(dimethylsiloxane) (PDMS) based microfluidic devices have a wide range of applications in chemistry, biology, environmental science and drug delivery. PDMS devices, fabricated using soft lithography were utilized in fabrication and optimization of biotin-avidin protein bioassay. In order to …
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Bioanalytical applications of microfluidic devices
… the thesis describes a new patterning technique--microfluidic contact printing--that combines several of the desirable aspects of microcontact printing and microfluidic patterning and addresses some of their important limitations through the integration of a track-etched polycarbonate (PCTE) …
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Fabrication of Polymersomes using Microfluidic Devices
… acid) (PEG-b-PLA) by means of microfluidics is described. The experiments were performed in microfluidic devices made by soft lithography in poly(dimethylsiloxane) (PDMS). To gain insight into the fluid dynamics in the microfluidic devices, 2D and 3D simulations based on the …
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Microbead-Based Biosensing in Microfluidic Devices
… sample. The integration of microbeads into microfluidic systems for biological testing is an area of growing interest. Such "lab-on-chip" systems are designed to integrate several functions of a conventional laboratory onto a single chip. As a platform to capture targets, beads offer several …
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Membrane-Based Protein Preconcentration Microfluidic Devices
… of the small (~pL) detection volumes in these devices. I have made membrane-based protein preconcentration systems in capillary and microchip designs to increase the detectability of low-concentration biological samples. A photopolymerized ion-permeable membrane interfaced with a microchannel …
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Simulating DNA behavior in microfluidic devices
… last twenty years, however, the appearance of microfluidic devices, whose smallest length scales are comparable to the size of a polymer molecule, has offered ways to visually study the behavior of individual polymer molecules and made possible new and exciting applications that exploit the …
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Microassembly technology for modular, polymer microfluidic devices
Assembly of modular, polymer microfluidic devices with different functions to obtain more capable instruments may significantly expand the options available for detection and diagnosis of disease through DNA analysis and proteomics. For connecting modular devices, precise, passive alignment …
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Passive and active control for microfluidic devices
Includes bibliographical references (pages 50-54).
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Maskless photopatterning of cells in microfluidic devices/
Upon examining current methods for printing and patterning of live biological cells, there is a need for a method capable of printing with the resolution of single biological cells to organize them into complex structures. In order to fill this need, building upon previous design of a dynamic …
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Fabrication of microfluidic devices for artificial respiration
… elastomeric polydimethylsiloxane (PDMS) microfluidic devices incorporated with photoactive thin films to create an implantable artificial respiration platform. Whereas state-of-the-art respiration support machines deliver oxygen gas directly to the blood via external macroscale devices, …
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Fabrication of Polymeric Microfluidic Devices for Protein Analysis
… PMMA micro capillary electrophoresis (µCE) devices made with the covalently modified surfaces exhibited substantially reduced electroosmotic flow and nonspecific adsorption of proteins. Both column efficiency and migration time reproducibility were one order of magnitude better with …
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Characterization of fluid flow in paper-based microfluidic devices
Paper-based microfluidic devices are being leveraged for application of diagnostic and detection technology in low-resource settings. In order to design a highly accurate device, a mathematical model is required to predict flow behaviour in the paper-based microfluidic devices. A series of …
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High fidelity simulations of electrokinetic phenomena in microfluidic devices
… applied electric fields, electrokinetic micro-devices allow for innovative functionality in a wide range of microfluidic applications including sample injection, separation, rapid micromixing, and miniaturized chemical and biochemical analysis and detection. This dissertation focuses on …
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ELECTROKINETIC SEPARATIONS ON MICROFLUIDIC DEVICES FOR N-GLYCAN PROFILING
Microfluidic devices have been employed for various chromatographic and electrophoretic separations of biomolecules. However, the inherent complexity of analyzing real biological samples requires faster and more efficient separation techniques. N-glycans are essential molecules in many living …
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Magnetic forces for surface-based bioanalysis in microfluidic devices
… utilised in the field or at the point-of-care. Microfluidic technology has gone some way to producing such systems, however many of the current devices still incorporate batch methods of analysis, which are still time consuming or do not integrate all steps of the analysis on one device.Two …
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Microfabrication and Evaluation of Planar Thin-Film Microfluidic Devices
Over the past 15 years, research in the field of microfluidics has rapidly gained popularity. By seeking to miniaturize and automate separation-based analysis, microfluidic research seeks to improve current methods through decreased cost, analysis time, and sources of contamination. My work has …
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Metering and Routing of Liquid Quanta in Microfluidic Devices
… thesis describes the development of a number of microfluidic handling techniques, including; (i) the detection of individual liquid droplets using electrical position sensors; (ii) the generation and control over the three major microfluidic segmented laminar flow regimes; (iii) the creation of …
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