Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 43 for “"Microcrystalline cellulose"”.
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Chlorhexidine Interaction with Microcrystalline Cellulose
… stains due to chemical interactions with cellulose fibers. Previous research has identified compounds such as Parachloroaniline (PCA), which contribute to both toxicity and fiber degradation. This study aims to further analyze the breakdown products of chlorhexidine and sodium hypochlorite …
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Effect of surface modifications on biodegradation of nanocellulose and microbial response
… on in product development. In particular, nanocellulose is touted as a promising green nanomaterial, as it is sourced from an effectively inexhaustible feedstock of wood-based cellulose and is assumed to be harmless to the environment since it is derived from a natural material and assumed to …
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Bio based photocurable polymers for advanced applications
… photo-curable materials based on waste-derived cellulose, addressing the environmental and sustainability challenges associated with conventional fossil-based polymers. Cellulose, the most abundant natural polymer, was selected as a renewable feedstock due to its availability, structural …
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Small scale manufacturing and scintigraphic detection of pellet formulations
… studies.Extrusion-spheronisation used microcrystalline cellulose and lactose as the main components. Thermally controlled spheronisation at elevated temperature produced pellets within a narrow size distribution. It was found that the drug release rate from extrusion-spheronised pellets …
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Development and evaluation of oral solid dosage forms for colonic delivery of drugs for the treatment of cystinosis.
… tested include starches, natural gums and cellulose derivatives. The study evaluated the properties of each wet mass formulation, extrudate and spheronisation product that were obtained, subsequently comparing them to those obtained from a standard extrusion aid - microcrystalline …
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ΑΝΑΠΤΥΞΗ ΤΕΧΝΙΚΩΝ ΓΙΑ ΤΗ ΒΕΛΤΙΩΣΗ ΤΗΣ ΠΟΙΟΤΗΤΑΣ ΤΩΝ ΔΙΣΚΙΩΝ ΚΑΙ ΤΗΝ ΑΠΟΔΕΣΜΕΥΣΗΦΑΡΜΑΚΩΝ ΑΠΟ ΕΠΙΚΑΛΥΜΜΕΝΕΣ ΣΤΕΡΕΕΣ ΦΑΡΜΑΚΟΤΕΧΝΙΚΕΣ ΜΟΡΦΕΣ
… (II) A NEW AQUEOUS SYSTEM CONSISTED OF AGAROSE, MICROCRYSTALLINE CELLULOSE, HYDROXY- PROPYL METHYL-CELLULOSE (H.P.M.C) AND PEG-1000 YIELDS A MECHANICALLY STRONG, FLEXIBLE FILM THAT ATTACH ONTO THE SURFACE OF THE TABLETS. CRITICAL EVALUATION OF THE FREE FILMS REVEALED THAT SUCH FILMS ABSORB …
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Formulation of oral dosage forms by three dimensional printing
… known as three dimensional printingTM (3DPTM). A microcrystalline cellulose powder was used in combination with pH-dependent and permeable polymeric binder solutions. Release studies in acidic media were performed using both dye and drug (antihistamine) as actives. Deposition was performed by …
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Theoretical and experimental investigation of particle interactions in pharmaceutical powder blending
… electrostatic force of lactose monohydrate and microcrystalline cellulose were measured by the atomic force microcopy and other techniques. Their correlations with particle properties and environmental variables were elucidated quantitatively through mathematical modeling, and their impacts on …
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Regime map development for co-rotating twin screw granulation
… [1], the same materials were chosen (MCC (Microcrystalline cellulose) 102 and aqueous Polyethylene Glycol (PEG) 6000) and the regime maps were plotted by following similar operating conditions with reference [1]. One regime (granulation behaviour) was recognised for the short mixing …
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Use of Aloe vera and Aloe marlothii materials as excipients in beads produced by extrusion–spheronization
Microcrystalline cellulose (MCC) is the most commonly used excipient in the manufacture of spherical particles or beads by extrusion spheronisation. However, the use of MCC in beads has its limitations such as prolonged release of drugs due to lack of disintegration. The aim of this study was to …
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Effect of flour protein content on the utilization of shortening and cellulose in biscuits
… and 50 grams of shortening and 0 or 2.2 grams of microcrystalline cellulose (MCC). Biscuit quality was assessed by objective and sensory evaluation. The caloric content of the biscuits was also determined by bomb calorimetry. No significant differences were detected in biscuit volume, crumb and …
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The effect of speed of compression on the properties of compacts.
… and the speed of compression. For ibuprofen microcrystalline cellulose mixtures positive interactions were considered to occur due to bonding between the two materials. For ibuprofen and lactose mixtures the interactions observed were considered to be a balance between the plastic deformation …
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High-Yield Cellulosic Hydrogen Production by Cell-Free Synthetic Cascade Enzymes: Minimal Bacterial Cellulase Cocktail and Thermostable Polyphosphate Glucokinase
… cellobiohydrolase was investigated on microcrystalline cellulose (Avicel) and regenerated amorphous cellulose (RAC). The optimal ratios for maximum cellulose digestibility were dynamic for Avicel but nearly fixed for RAC. Processive endoglucanase CpCel9 was most important for high …
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Low Frequency Dielectric Investigations on Hydrated Pharmaceutical Powders
… facilitate dielectric measurements on hydrated microcrystalline cellulose (MCC) and hydrated lyophilised proteins (papain, ovalbumin, pepsin and lysozyme) in the high millihertz to low megahertz frequency range. These materials are representative of two pharmaceutical technologies, viz. …
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Chemical Modification of Cellulose Fibers and their Orientation in Magnetic Field
… technique for orientating natural fibers like cellulose in a viscous polymer matrix such as polylactic acid (PLA) by applying the concepts of magnetism. Orientation of cellulose fibers in a PLA was achieved by modifying the cellulose fibers with a ferromagnetic entity and subjecting to a …
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Investigation of Copper Wire-Mediated Controlled/Living Radical Polymerization
… CLRP with EBiB was evaluated for grafting to cellulose substrates, microcrystalline cellulose and cellulose acetate. Cellulose was functionalized with thiol groups using ring opening reaction with ethylene sulfide. The grafting via thio-bromo click reaction was investigated, where grafting of …
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Apparent dissolution rate enhancement of poorly-water soluble drugs by adsorption technique
… DMF, DMSO and PEG400 were used as solvents and microcrystalline cellulose was used as an adsorbent. Pure model drugs, physical mixtures and prepared composites were characterized by using FTIR, DSC, XRD and dissolution testing. Results showed that the composites prepared with solvents DMF, DMSO …
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Effect of nano- fillers on tensile properties of biopolymer films
… must meet this requirement. In this study, microcrystalline cellulose (MCC), nanocrystalline cellulose (CNC), CaCO3 nanoparticles, hydrophilic nanoclay and hydrophobic nanoclay were separately added as fillers to the polymers, konjac glucomannan (KGM), hydroxypropyl methylcellulose (HPMC), …
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