Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 27 for “"Microbiome Analysis"”.
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A Transformer-Based Foundation Model for Human Microbiome Analysis
The human microbiome plays a crucial role in maintaining our health. Alterations in the microbiome have been linked to various chronic conditions like autoimmune disorders, metabolic diseases, and cancer. While various tools have been developed to study the microbiome, each tool tends to be …
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A comprehensive microbiome analysis of wheat and its wild relatives
Microbiomes are diverse assemblages of endophytic and free-living microorganisms that can confer competitive advantages to their plant hosts such as water acquisition, nutrient mobilization, drought tolerance, salt tolerance, and disease resistance (Chaparro et al., 2012; Sherameti et al., 2008; …
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AUGMENTING SEQUENCING TECHNOLOGY FOR BETTER INFERENCE IN SOIL MICROBIOME ANALYSIS
… of DNA sequencing revolutionized the field of microbiome research. Many organisms, by virtue of their codependence and/or growth rate, are either impossible or extremely challenging to get into pure culture. Sequencing allows important taxonomic and phylogenetic information to be obtained …
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GENOMIC AND MICROBIOME ANALYSIS TO IMPROVE FILLET YIELD AND QUALITY TRAITS IN RAINBOW TROUT
… to as “missing heritability.” Recently, the gut microbiome has emerged as a potential contributor to phenotypic variation through host–microbiome interactions. Some microbiome features may be heritable, which could help account for portions of the missing heritability. In this study, we …
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Development of methods for the microbiome analysis of formalin fixed paraffin embedded tissue specimens
… can be engineered. The remarkable influence our microbiome has on our health status has made it a focus of attention for engineering possibilities aiming at its modulation. As the field of the human microbiome expands, it necessitates access to high-quality nucleic acid samples which are truly …
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Life history and microbiome analysis of freshwater fingernail clams (sphaeriidae) exposed to trace metal pollution
<p>Aquatic habitats impacted by anthropogenic activities such as mining can contain metal mixtures of nonessential and essential trace metals. The consequences of chronic exposure to metal mixtures on the life history of benthic organisms are unclear, as are the potential effects on host-associated …
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Machine learning methodologies for high dimensional biomedical & bioinformatics applications
… the context of text mining, computer vision and microbiome analysis. To address the different challenges in these applications, novels methods in matrix factorization, image registration, and deep learning are proposed. For the first project on text mining, we propose the semi-orthogonal …
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Impact of dietary functional yeast additives on growth performance and health of selected key aquaculture species
… gene expression, and intestinal 16S rRNA microbiome analysis. Three experimental in vivo feeding trials were undertaken on three key aquaculture species, including Nile tilapia (Oreochromis niloticus), mirror carp (Cyprinus carpio), and Atlantic salmon (Salmo salar) under controlled and …
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Modifikuotų nukleotidų taikymas plataus masto nukleorūgščių analizei /
… described in the dissertation include novel microbiome analysis technique st16S-seq and novel gene expression analysis method MTAS-seq. Taken together, this work suggests OTDDNs as a promising tool for high-throughput nucleic acid analysis.
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The utility of modified nucleotides for high-throughput nucleic acid analysis /
… described in the dissertation include novel microbiome analysis technique st16S-seq and novel gene expression analysis method MTAS-seq. Taken together, this work suggests OTDDNs as a promising tool for high-throughput nucleic acid analysis.
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Addressing geometric abnormalities and algorithmic shortcomings in metagenomic analysis.
Our work aims to identify shortcomings in microbiome analysis methods, making maximal use of sequencing data output to accurately represent sample relationships in a microbiome dataset. We introduce LMdist, a dimensionality reduction method for adjusting pairwise distances to more accurately …
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Design and Commercialization Strategy of a Gantry-Based Automation Platform for High-Throughput Raman Spectroscopy
… that enables rapid, label-free molecular analysis. This offers significant potential to be used across pharmaceutical development, microbiome research, and food diagnostics. However, the utility of Raman spectroscopy in high-throughput applications has been limited by the lack of …
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Effect of Yeast Supplementation During Various Stages of Beef Production
… weaning to the end of the backgrounding period. Microbiome analysis found that supplemental yeast did not dramatically change α or β diversity nor was there a difference in community structure for rumen bacteria; fecal α or β diversity were different on d 34. In experiment 3, late gestation cows …
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Understanding the impact of Russian wheat aphid-associated microbes on plants
… systems. Through a combination of proteomics, microbiome analysis, transcriptomics and biological assays, this work provides novel insights into how aphid-associated microbes contribute to the amount of damage aphids cause to plants (aggressiveness) and alter plant hormone signaling. In Chapter …
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Follow your gut: Does AKR1D1 impact gastrointestinal health?
… X receptor (FXR) affinity. Accordingly, RNAseq analysis revealed a decrease in the mRNA levels of key antioxidant and FXR target genes in the ileum. Although caecal microbiome analysis showed no change in total phylum bacterial counts and key markers of dysbiosis (ratio of Firmicutes to …
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An integrated multi-omics approach to improve our understanding of ageing and neurodegeneration
… functionally activated by the first colonising microbiome at birth. In this research project, we have developed a computational framework to independently analyse single-nucleus transcriptomics and shotgun metagenomics data types along with their integration at the pathway level. From our …
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The association of early childhood nutrition and growth with the intestinal microbiome and pneumonia
… significantly to under-5 mortality. The gut microbiome is associated with development of malnutrition and pneumonia. However, data on longitudinal growth, infant feeding practices, and the microbiome in children with malnutrition and pneumonia in low and middle-income countries (LMIC) are …
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The association of prematurity and medical conditions with the gut microbiome of mammals
Rapid development in the microbiome field has accelerated the identification of association between the microbiome and the host. Early-life microbial seeding has been suggested to impact health later in life, and a breakdown in the development of the host:microbiome relationship is thought to …
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Enabling the Development of Sustainable Aquaculture in Qatar
… and aquaculture setting for the hamour using a microbiome approach. For both atlases, the histological analysis was conducted for nine organs including the skin and muscle, gill, liver, intestine, male and female gonads, heart, kidney, and spleen, (excluding skin for hamour). These atlas …
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