Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 732 for “"Microbiome"”.
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Insights into the primate microbiome
Limited Restriction Lifted for Item 114016 on 2022-03-03T10:15:08Z.
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Causal Inference Methods for Microbiome Data
… for advancing causal mediation analysis in microbiome research. Microbiome data are characterized by high dimensionality, sparsity, overdispersion, and strong interdependencies, making conventional mediation approaches ill-suited for reliable inference. Existing methods often fail to deliver …
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Engineering the gut microbiome of honey bees
… use. These bees house a simple, conserved gut microbiome that is important for their health. Can we use this gut microbiome to protect bees in new ways? Synthetic biology combines recombinant DNA technology and rational design principles to redesign biological processes. Microbiome engineering …
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Characterization of the vaginal microbiome in pregnancy
The vaginal microbiome plays an important role in women's reproductive health. Imbalances in this microbiota are associated with bacterial vaginosis, increased susceptibility to sexually transmitted infections, and negative reproductive outcomes. The causes of such variations, however, are poorly …
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Microbiome-centered Approaches to Marine Disturbance Ecology
… the research that has been performed on marine microbiome responses to perturbation has been limited to the a priori identification of disturbances, limiting the scope of current research to events considered disturbances from the researchers’ perspective (e.g. hurricanes, contamination, etc.). …
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The mucosal microbiome of inflammatory bowel diseases
The human microbiome is the diverse community of micro-organisms that live with humans. The gut microbiome contains the densest collection of microbial cells in the body and has been described as functioning as an organ. Alterations in these microbial communities are associated with disease. This …
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Legume-rhizobia interactions in a complex microbiome
… and strain behaviour when exposed to a complex microbiome. To identify some these differences, this experiment applies two treatment factors in a controlled environment of containers with autoclaved sand. All main experimental containers were inoculated with several strains of Bradyrhizobia …
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Legume-rhizobia interactions in a complex microbiome
… and strain behaviour when exposed to a complex microbiome. To identify some these differences, this experiment applies two treatment factors in a controlled environment of containers with autoclaved sand. All main experimental containers were inoculated with several strains of Bradyrhizobia …
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Evolution of the blood microbiome in primates
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2024-05-01
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Comparative analysis of methods for microbiome study
This Thesis was approved for publication on 2020-07-08 at 09:48.
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Evolutionary dynamics of the human gut microbiome
The composite members of the human gut microbiome encounter a myriad of selective pressures from the host environment and other microbial members in the ecosystem. Understanding the evolutionary dynamics of microbial species in the gut microbiome requires sequencing information that differentiates …
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Mining the human microbiome for clinical insight
The human microbiome is essential for health and has been implicated in many diseases. DNA sequencing has enabled the detailed characterization of these human-associated microbial communities, leading to a rapid expansion in studies investigating the human microbiome. In this thesis, I describe …
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The Gut Microbiome: Is Fecal Matter Microbial Composition a Proxy for Intestinal Microbial Composition in Studies of the Microbiome
… to be affected directly and indirectly by the microbiome, gut microbiome research has increased in the last decade. Issues such as allergies, cancer, obesity, and other health complications have been shown to be influenced by the microbiome. Most of gut microbiome research is done by collecting …
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The Effect of the Microbiome on DNA Methylation
… the DNA methylomes of germ-free (GF; no microbiome) and specific pathogen free (SPF; controlled microbiome) mice were analyzed with a DREAM assay. This was done in wild-type mice and in IL-10 KO mice, with or without the addition of the colitis-associated cancer inducing compound, …
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Interplay between selenium hyperaccumulator plants and their microbiome
The plant microbiome includes all microorganisms that occur on the plant root (rhizosphere) and shoot (phyllosphere) or inside plants (endosphere). Many of these microbes benefit their host by promoting growth, helping acquire nutrients or by alleviating biotic or abiotic stress. In addition to its …
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Investigating the lignocellulolytic gut microbiome of huhu grubs
… of structure and composition of the gut microbiome of huhu grubs reared on cellulose or lignocellulose diets, along with isolation of novel lignocellulolytic isolates could prove to be significant for the biofuel industry.
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Microbiome and Metagenomics: Statistical Methods, Computation and Applications
… also presents two novel statistical models for microbiome data analysis. One important aspect of metagenomic data analysis is to quantify the bacterial abundances based on the sequencing data. In order to account for certain systematic differences in read coverage along the genome, we propose a …
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Étude et ingénierie du microbiome de cannabis sativa
… intensives et durables via l’ingénierie du microbiome de la plante pourrait présenter des avantages économiques et écologiques importants pour ce secteur. Quoique la culture de C. Sativa soit généralement bien maitrisée, la riche complexité du microbiome de la plante reste encore à ce jour à …
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Assessment of the microbiome associated with endangered orchids
… this study, we sought a broader picture of the microbiome associated with these plants. A major motivation for our work is the concern that the gaps in our understanding of orchid microbiomes might have important consequences when decisions are made in the management of species of conservation …
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