Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 51 for “"Microbial metabolism"”.
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Probabilistic Reconstruction and Comparative Systems Biology of Microbial Metabolism
With the number of sequenced microbial species soon to be in the tens of thousands, we are in a unique position to investigate microbial function, ecology, and evolution on a large scale. In this dissertation I first describe the use of hundreds of in silico models of bacterial metabolic networks …
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Coarse-grained modeling of microbial metabolism in model and non-model yeasts
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2026-05-01
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Linking microbial metabolism and organic matter cycling through metabolite distributions in the ocean
… not been well characterized and their roles in microbial physiology, ecological interactions, and carbon cycling remain largely unknown. In this dissertation metabolomics techniques were developed and used to profile and quantify a suite of metabolites in the field and in laboratory experiments. …
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Linking microbial metabolism and organic matter cycling through metabolite distributions in the ocean
… not been well characterized and their roles in microbial physiology, ecological interactions, and carbon cycling remain largely unknown. In this dissertation metabolomics techniques were developed and used to profile and quantify a suite of metabolites in the field and in laboratory experiments. …
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Development of Steady-State and Dynamic Flux Models for Broad-Scope Microbial Metabolism Analysis
… examining cell flux distributions in the central metabolism. FBA, on the other hand, gives a holistic review of optimal fluxomes on the genome scale. In this dissertation, flux analysis techniques were constructed to investigate the microbial metabolisms.</p> <p>First, an open-source and …
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The effect of freeze /thaw temperature fluctuations on microbial metabolism of petroleum hydrocarbon contaminated Antarctic soil
… in temperature may be most detrimental to microbial activity.</p><p>This research evaluated the biodegradation of petroleum contaminated Antarctic soil at a low stable temperature (7°C). It also evaluated temperature fluctuations. This was accomplished through experiments using …
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Identification of branch-point restrictions in microbial metabolism through metabolic flux analysis and local network perturbations
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 1991.
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Development and Application of Fluxomics Tools for Analyzing Metabolisms in Non-Model Microorganisms
Decoding microbial metabolism is of great importance in revealing the mechanisms governing the physiology of microbes and rewiring the cellular functions in metabolic engineering. Complementing the genomics, transcriptomics, proteinomics and metabolomics analysis of microbial metabolism, fluxomics …
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Metabolic and Kinetic impacts of the auxiliary energy source in model chemolithoheterotrophic Bacteria
Chemolithoheterotrophy describes a type of microbial metabolism by which organisms oxidise an inorganic electron donor to supplement the generation of an electrochemical gradient. This results in higher overall growth yields and maximum specific growth rates as the organism does not need to …
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Colonic metabolism of dietary grape seed extract: Analytical method development, effect on tight-junction proteins, tissue accumulation, and pan-colonic pharmacokinetics
… unabsorbed and reaches the colon where extensive microbial metabolism occurs. The objectives of these studies are to better understand the roles and activities of PCs in the lower gastrointestinal tract. First, a new high-throughput Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry …
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Characterizing the higher order metabolism of oral streptococci
The metabolism of microbial species is very diverse, displaying a wide range of capabilities. This diversity is often explainable by differences in the metabolic networks that underly microbial metabolism. However, closely related microbial species that have structurally conserved metabolic networks …
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The science and politics of increasing nitrogen pollution from human activity : case study of the Aberjona watershed
… zones" of hypoxia found throughout the world. Microbial metabolism of nitrogen via the nitrification and denitrification pathways also produces N20, a potent greenhouse gas currently responsible for 5% of total atmospheric radiative forcing.
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Coagulation study of a bound water bulked sludge
… content. The effect of coagulant addition upon microbial metabolism was studied using dissolved oxygen uptake. Coagulant dosages ranging from 200 mg/l to 700 mg/l were added to 1000 mg/1 and 2000 mg/l mixed liquor volatile suspended solids (MLVSS) concentration sludges, while dosages ranging …
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Kinetics of Microbial Respiration
… a thermodynamically consistent rate law for microbial respiration. Previous approaches to predicting the rate of microbial respiration have relied on empirical relations, such as the Monod and dual-Monod equations, which do not consider how energy available in cell's environment or the …
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Microbial respiration on decaying leaves and sticks along an elevational gradient of a southern Appalachian stream
Microbial respiration on sticks and leaves, measured as oxygen uptake rate, was compared among four (2nd-4th order) sites along an elevational gradient at Coweeta Hydrologic Laboratory, North Carolina. Rhododendron and birch leaves were placed in mesh bags in the stream at each site on 21 Oct 90. …
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Linking Carbon Dynamics in Stream Ecosystems to Dissolved Organic Matter Quality
… conditions demonstrate that DOM quality governs microbial metabolism (i.e. respiration and bacterial protein production). Moreover, I revealed significant quality differences between two terrestrial DOM sources, while respiration and bacterial protein production increased with the available …
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Microbial Diversity and Geochemical Energy Sources of Tutum Bay, Ambitle Island, Papua New Guinea, an Arsenic-Rich, Shallow-Sea Hydrothermal System
… in Tutum Bay, significant amounts of energy for microbial metabolism could be gained from a number of reactions, including AsIII oxidizing reactions using oxygen and nitrate as terminal electron acceptors. In the third chapter, a 16S rRNA-based culture-independent investigation of the archaeal …
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Cryogenic carbon cycling at an Icelandic glacier
… tonnes per year). Evidence suggests subglacial microbial acetoclastic methanogenesis is responsible with δ13C and δD CH4 values of ~60‰ and -320‰ respectively, supported by laboratory identification of methanogenesis in Sόlheimajökull subglacial sediments. The organic counterpart to the carbon …
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The effect of alternative electron acceptors on the subsurface biodegradation rates of methanol and tertiary-butyl alcohol
… stabilize it against the acidic by-products of microbial metabolism. The addition of nitrate resulted in increases in the initial rates of degradation of methanol ranging from 20 to 1040 percent. After a period of time, however, an inhibitory build-up of nitrite generally occurred, essentially …
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Modeling for microbial communities with cross-feeding and predator-prey interactions
Microbial communities exist nearly everywhere on our planet, from extreme environments such as hydrothermal vents to host environments like the human gut, where microbes interact in diverse ways, such as resource competition and predator-prey interactions. In ecology, mathematical models have been …
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