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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 10 of 10 for “"Microbial cell factories"”.
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Production of a functional human milk oligosaccharide, 2'-fucosyllactose, using microbial cell factories
… an alternative route to produce 2-FL using a microbial cell factory was devised. First, E. coli, as a host strain to produce 2-FL, was engineered to overexpress genes in the metabolic pathway of GDP-L-fucose, a donor of L-fucose, and harbor the fucosyltransferase enzyme (FucT2) which catalyzes …
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Systems Metabolic Engineering of Microbial Cell Factories for the Synthesis of Value-added Chemicals
<p>Microbial cell factories offer us an excellent opportunity for the conversion of many different cheaply available raw materials into valuable chemicals. Systems metabolic engineering aims at developing rational strategies for the engineering of microbial hosts by providing global level …
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Accelerating the design-build-test-learn cycle for the development of microbial cell factories
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2024-12-01
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Discovery of a Novel Microalgal Strain Scenedesmus Sp. A6 and Exploration of Its Potential as a Microbial Cell Factory
… challenges involving the use of microalgae as microbial cell factories. To investigate the application of anaerobic digestion as a way to generate nutrients for microbial growth, salmon offal was used as substrate for anaerobic digestion, and soil from a flooded run-off pond on the Virginia …
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Development of 13C Fingerprint Tool and Its Application for Exploring Carbon and Energy Metabolism in Cyanobacterium Synechocystis sp. PCC 6803
<p>Cyanobacteria are important microbial cell factories that are widely used in the biotechnology filed nowadays. They can use light as the sole energy source to fix CO2, accumulate biomass, and produce various valuable bio-products. Engineered cyanobacterial species can uptake nutrients from …
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On the Effectiveness and Challenges of Electrosynthesis Strategies in Escherichia coli
… this work is to examine several strategies for microbial electrosynthesis, the delivery of electrical energy to microbial cell factories, for producing chemicals. The study encompasses four areas type of microbial electrosynthesis and the results are summarized here: 1) Experimental work was …
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Development of Steady-State and Dynamic Flux Models for Broad-Scope Microbial Metabolism Analysis
… characterize carbon and energy flows through a cells metabolic network. By employing both 13C-labeling experiments and nonlinear programming, 13C-MFA provides a rigorous way of examining cell flux distributions in the central metabolism. FBA, on the other hand, gives a holistic review of optimal …
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Elucidation of weak organic acid resistance mechanisms in non-Saccharomyces yeast: a case study of Zygosaccharomyces parabailii and Kluyveromyces marxianus
… sustainable source of feedstock and robust microbial factories. Among others, lignocellulose and whey, which are residual wastes deriving from wood/agriculture and dairy industries, represent cheap, sugar-enriched feedstocks. The conversion of lignocellulose and whey into the desired …
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Genome engineering in saccharomyces cerevisiae
Microbial cell factory, which converts biomass feedstock to value-added compounds such as fuels, chemicals, materials and pharmaceuticals, has been proposed as a sustainable and renewable alternative to the traditional petrochemical industry. Saccharomyces cerevisiae is one of the most widely used …
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Novel Electron Transfer Systems in Hyperthermophilic Methanogenic and Anaerobic Methanotrophic Archaea: F420-dependent Nitrite Reductase and [Fe-S] Cluster Assembling Thioredoxin
… expanded the boundaries of our knowledge about microbial energy conservation and opened the potential for bioinspired catalysts. They have also garnered attention as potential microbial cell factories for value-added products. Considering their prospects in science, technology, and engineering, …