Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 3 of 3 for “"Microarray patches"”.
-
Lymph-targeted intradermal delivery of antiretroviral agents via dissolving polymeric microarray patches
… come with many drawbacks. Dissolving polymeric microarray patches (MAPs) are minimally-invasive and self-disabling delivery systems that can be employed for intradermal administration of various compounds. This thesis explores, for the first time, the lymph-targeted intradermal delivery of the …
-
Transdermal delivery of heavy chain only antibody binding domains using hydrogel-forming microarray patches
… and Nanobody® molecules using hydrogel-forming microarray patches (MAPs). Using this MAP technology, both HCAbs could permeate through dermatomed (350 µm) neonatal porcine skin in vitro. Furthermore, two Nanobody® molecules were successfully delivered in a Sprague Dawley rat model for the first …
-
Preclinical evaluation of dissolvable microarray patches for allergy treatment: key factors governing in vitro and in silico assessment
… with innovative platforms such as dissolvable microarray patches (MAP), offering the potential for targeted local and systemic drug effects. However, no dissolvable MAP have yet reached the market. Despite significant advances in early MAP development (e.g. materials, fabrication), critical …