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Showing 1 to 2 of 2 for “"MicroRNA-29"”.
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The roles of the microrna 29 family in cartilage homeostasis and osteoarthritis
MicroRNAs are short endogenous non-coding RNA molecules, typically 19-25 nucleotides in length, which negatively regulate gene expression. In osteoarthritis (OA), several genes necessary for cartilage homeostasis are aberrantly expressed, with a number of miRNAs implicated in this process. However, …
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Role of MicroRNA-29 and ADAM12 in the Regulation of REST Dependent Signaling Pathways in Uterine Fibroids
… expression in leiomyomas could be linked through microRNA-29 (miR-29). In addition, in cultured mammary tumor cell lines, miR-29 is known to directly regulate ADAM12 expression. Compared to normal myometrium, uterine fibroids express significantly lower levels of miR-29. In its promoter, miR-29 …