Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 44 for “"Micro-fluidic"”.
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Micro fluidic cytometry for analysis of marine microorganisms
… distribution and concentration of phytoplankton (microscopic algae that live in the oceans) is important, as this reflects and may modify environmentally important events such as pollution, climate change and carbon dioxide sequestration. Optical based flow cytometry has proved to be strategically …
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Numerical Simulations of Flow and Mass Transport in Micro-Fluidic Components for Modular Bio-Analytic Chip Applications
Microfluidics has received a great deal of attention in the past decade. The ability of modular microfluidic chips to miniaturize integrate chemical and biological systems (µTAS) can be greatly productive in terms of cost and efficiency. During the design of these modular devices, misalignment of …
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Characterization of Pressure-Driven and Electro-Kinetically Driven Flow in a Micro-Fluidic Chip Using Particle Imaging Velocimetry
… electro-kinetic driven flows were compared for a microfluidic chip. It was found that the pressure-driven flow had a parabolic profile while the electro-kinetic flow had a plug shaped flow profile. The measured velocities were similar to those determined by the Poiseuille flow model and the …
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Ion Current Rectification in Nano/Micro-Fluidic Interfaces and Pulsed Glow Discharge Time-of-Flight Mass Spectrometric Chemical Speciation
Microfluidics continues to be of interest for analyzing chemical and biological samples because of the disposability, portability, low sample consumption, fast analysis time, and parallel analysis potential for multiple samples in a single device. To improve microfluidic device functionality, …
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Development of micro fluidic based devices for studying tumour biology and evaluating treatment response in head and neck cancer biopsies
… response of tumours from distinct sites.Micro fluidics relates to the science of systems that process or manipulate small amounts of fluids within micro channels. When applied in biology, the technology enables the production of simple, robust and highly versatile systems for studying …
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Design of a micro-Functional Testing System for process characterization of a hot micro-embossing machine
… commercial, and medical applications for micro-fluidic devices has fueled heightened research and development into micro-fluidic design, materials, and increasingly manufacturing. Polymers (Poly(methyl methacrylate)-PMMA in particular) are the current material of choice given their low …
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Development of an electro-kinetically driven integrated DNA profile separation and detection system
… which has been successfully performed within a micro-fluidic environment; however integration of each of the different procedures onto a single device has not been documented. This thesis presents briefly the application of a gel supported reagent matrix to aid in the integration of DNA …
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Controlled loading of cryoprotectants (CPAS) with cell volume constraints
… Due to the large size of oocytes that requires microscopy methods which could be difficult to implement, micro fluidic device is presented in this study based on Coulter-principle to simultaneously control and measure the volume of a single cell. In this thesis we designed and fabricated a micro …
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Electro-Thermal Codesign in Liquid Cooled 3D ICs: Pushing the Power-Performance Limits
… Hence better cooling solutions are necessary. Micro-fluidic cooling, which integrates micro-channel heat sinks into silicon substrates of the chip and uses liquid flow to remove heat inside the chip, is an effective active cooling scheme for 3D-ICs. While the micro-fluidic cooling provides …
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Direct-Write Assembly of Three-Dimensional Polyelectrolyte Scaffolds, Inorganic Hybrids, and Photonic Crystals
… architecture are created by replicating 3D microperiodic polymer scaffolds assembled by direct ink writing. First, polymer woodpiles with a face-centered tetragonal geometry are fabricated by direct ink writing. Chemical vapor depositions of silica and germanium are then performed under …
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Process window and variation characterization of the micro embossing process
The micro embossing process on polymethylmethacrylate (PMMA) is demonstrated experimentally to be a useful process to produce micro fluidic and optical devices. Because this process is a one step thermoplastic deformation process, it is possible to reach high production rates and low cost in …
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Miniaturised analytical systems with chemiluminescence detection for environmental applications
This thesis details the use of microfluidic devices and chemiluminescence detection in order to develop a portable method of analysis for measuring chemical species in the environment.Chapter 1 outlines microfluidic technology, including fabrication techniques, fluid manipulation and mixing within …
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Pore-scale characterization of transverse mixing-induced calcium carbonate precipitation of relevance to geological carbon sequestration
… in an experimental model. This model is a small micro-fluidic device that incorporates a flow channel with an imprinted homogeneous pore structure to replicate the porous nature of groundwater flow. Sodium carbonate and calcium chloride were injected in to this model to form a calcium carbonate …
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Nonlinear Dynamics of Electrostatically and Magnetically Actuated MEMS
"The multi-physical nature of microelectromechanical Systems (MEMS) makes the development of CAD tools for MEMS a challenging area. Besides, the non-linear coupling between the different physical domains in MEMS can give rise to interesting non-linear dynamic properties. These non-linear …
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Microfluidic electrochemical sensors for the selective detection of toxic compounds
… based detection chemistries, as well as the micro-fluidic device platforms which enable these sensors to be operated in a practical, effective manner. The majority of the work in this thesis involves an aqueous based chemistry utilizing an oxime reagent for the detection of …
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Modeling, design, and fabrication of pulsed fluidic micro-actuators
… design, and fabrication of electrostatic micro fluidic actuators, which use the pulsing mechanism described above to generate a fluid flow. Particle Image Velocimetry (PIV) is used to visualize the jet at various drive frequencies. The complex coupling between the electric field driving …
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High aspect ratio electrodes for high yield electroporation of cells
… the cell membrane to kill the cells. Current micro-fluidic electroporation devices use the planar electrodes situated at the bottom of a microchannel. These planar electrodes i) require a high voltage and ii) generate a nonuniform electric field which result in low yield of the …
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On contractile force developed by the Spasmoneme, a biological spring of a peritrich ciliate Vorticella convallaria
… I apply viscous uid ow to Vorticella with a micro fluidic channel.
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Computational Methods for the Measurement of Protein-DNA Interactions
… locations is evaluated. Public data from a micro-fluidic experiment is used to fit a matrix model of binding specificity for a single transcription factor. Physical association and disassociation constants from the experiment enable a biophysical interpretation of the data to be made in this …
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Active lubricant-impregnated surfaces
… importance for diverse applications ranging from micro-fluidic devices, anti-icing, drop-wise condensation and biomedical devices, however most of the time droplets are moved passively. The use of active external fields has been explored via electric, acoustic and vibrational fields, yet moving …
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