Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 10 of 10 for “"Micro-Total-Analysis systems"”.
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Towards Early State Disease Detection in Microdevices: Fabrication and Testing of Micro Total Analysis Systems for Bioanalytical Applications
… the entire complement of proteins, or proteome. Micro total analysis systems (μTAS) are an emerging promising method, offering rapid, sensitive and low sample consumption separations. I have demonstrated microchip capillary electrophoresis (CE) devices made of CaF2. New methods have been …
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Single Cell Impedance Measurements Using Microfabricated Electrodes and Labview Graphical Programming
… electrical properties, along with background in micro-total-analysis systems as well as impedance spectroscopy. Experimental Methods are then discussed for the electrode design, cellular modeling in COMSOL, fabrication methods, and Labview 8.0 Set-up and programming. Measurements were performed …
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Mass transfer and structural analysis of microfluidic sensors
… of the natural high surface-to-volume ratios in microfluidic devices, low reagent consumption and high potential for integration in more complex micro total analysis systems (microTAS or pTAS). This thesis studies the fundamental limits of on-chip integrated microfluidic sensors. More …
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Electrokinetically Driven Mixing in a Microchamber for Lab-on-a-Chip Applications
Electrokinetically Driven Mixing in a Microchamber for Lab-on-a-Chip Applications Narayan Sundaram Abstract Micro-Total-Analysis-Systems (μTAS) have been the focus of recent world wide research due to their varied applications. Much of the motivation for the development of μTAS stems from …
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High fidelity simulations of electrokinetic phenomena in microfluidic devices
… is the primary method of fluid handling in micro-total analysis systems. Under external applied electric fields, electrokinetic micro-devices allow for innovative functionality in a wide range of microfluidic applications including sample injection, separation, rapid micromixing, and …
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Integrating Micro-Scale Separations to Matrix Assisted Laser Desorption and Ioniation Time of Flight Mass Spectrometry (MALDI-TOF-MS) for Protein Analysis
This dissertation describes the integration of micro-scale separations to matrix assisted laser desorption and ionization time-of-flight mass spectrometry (MALDI TOF MS) for protein analysis. MALDI MS provides unsurpassed accurate mass measurements of intact bio-molecules, for example peptides and …
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Microchip Liquid Chromatography and Capillary Electrophoresis Separations in Multilayer Microdevices
In this dissertation, several microfabricated devices are introduced to develop new applications in the area of chemical analysis. Electrochemical micropumps, chip-based liquid chromatography systems and multilayer capillary electrophoresis microdevices with crossover channels were fabricated using …
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Detection of Proteins by Two-Photon Excitation of Native Fluorescence
… in a small volume, the trend in chemical analysis is toward micro total analysis systems (µTAS) or lab-on-a-chip devices. Among µTAS separation methods, the relatively new electric field gradient focusing (EFGF) technique has shown potential. It focuses and separates analytes based on …
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Marker-Free Isolation and Enrichment of Rare Cell Types Including Tumor Initiating Cells through Contactless Dielectrophoresis
Microfluidics has found numerous applications ranging from the life sciences industries for pharmaceuticals and biomedicine (drug design, delivery and detection, diagnostic devices) to industrial applications of combinational synthesis (such as rapid analysis and high throughput screening). Among …
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Development of an electrostatic peristaltic gas micropump and nanochannel fabrication technique
Microfluidics refers to devices and methods for controlling and manipulating fluid flows with length scales less than a millimeter. By miniaturizing the size, microfluidic systems lead to many benefits including decreased cost in manufacturing, use, and disposal; reduced consumption of expensive …