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Showing 1 to 6 of 6 for “"Mice--Genetics"”.

  1. Bent-tail a new mutation in the house mouse, Mus musculus

    Thesis (M.S.)--Michigan State College of Agriculture and Applied Science, 1937

    msu Repository record for Bent-tail a new mutation in the house mouse, Mus musculus (opens in a new tab)

  2. The Albino Mouse Visual System: How Perturbed Retinal Development Leads to Altered Binocular Projections

    … is altered in the VT retina of albino mice. This thesis further characterizes perturbations in RGC genesis and specification in the albino mouse. Analysis of retinogeniculate targeting in the albino mouse revealed a population of contralateral VT RGCS that forms an abnormal patch of …

    columbia-diss Repository record for The Albino Mouse Visual System: How Perturbed Retinal Development Leads to Altered Binocular Projections (opens in a new tab)

  3. Functional Characterization of Hippocampal Synapses in a Mouse Mutant of the Dystrobrevin Binding Protein 1 (DTNBP 1) Gene

    … of hippocampal synapses in sandy mice, which contain a spontaneous deletion in the DTNBP 1 gene resulting in the loss of expression of dysbindin, the protein that it encodes. I had observed enhanced excitatory basal synaptic transmission at the CA3-CA1 connection of juvenile mice, …

    columbia-diss Repository record for Functional Characterization of Hippocampal Synapses in a Mouse Mutant of the Dystrobrevin Binding Protein 1 (DTNBP 1) Gene (opens in a new tab)

  4. Aberrant assembly and function of a hippocampal circuit in a genetic mouse model of schizophrenia

    … the translocation. We created the Disc1Tm1Kara mice, an etiologically valid genetic mouse model which mimics the effect of the human translocation. Disc1 is highly expressed in the dentate gyrus of the hippocampus of adult mice, a region that is important for learning and memory. Disc1Tm1Kara …

    columbia-diss Repository record for Aberrant assembly and function of a hippocampal circuit in a genetic mouse model of schizophrenia (opens in a new tab)

  5. The Recruitment and Function of Tumor Microenvironment Components During Gastric Carcinogenesis

    … T lymphocytes and myeloid cells. K19kras mice express a mutant K-ras transgene in K19+ cells of the stomach; while K19 (and therefore the transgene) is not expressed in candidate stem/progenitor cells of the gastric corpus (marked by Dcamkl1 expression), a severe expansion and …

    columbia-diss Repository record for The Recruitment and Function of Tumor Microenvironment Components During Gastric Carcinogenesis (opens in a new tab)

  6. Characterization of 𝘈𝘵𝘩𝘴𝘲1, an Atherosclerosis Modifier Locus on Mouse Chromosome 4:

    … in humans. In this study we have used congenic mice that were previously constructed to isolate 𝘈𝘵𝘩𝘴𝘲1, an atherosclerosis susceptibility locus identified in a cross between MOLF/Ei and C57BL/6J-𝘓𝘥𝘭𝘳⁻⸍⁻. Atherosclerosis studies performed in congenic mice carrying the MOLF-derived susceptibility …

    columbia-diss Repository record for Characterization of 𝘈𝘵𝘩𝘴𝘲1, an Atherosclerosis Modifier Locus on Mouse Chromosome 4: (opens in a new tab)