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Showing 1 to 18 of 18 for “"Mice -- Physiology"”.
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Assessment of chromatin activity in mouse and human tissues
Pancreatic deoxyribonuclease preferentially digests active genes during all phases of the cell cycle including mitosis. Recently, a DNAse I-directed in ~ nick translation technique has been used to demonstrate differences in the DNAse I sensitivity of euchromatic and heterochromatic regions of …
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Immunogenicity of Staphylococcus Aureus Antigens Against Experimentally Induced Mastitis in the Mouse and Optimization of Antigen Production in Fermenter Culture
… 2-8 strains were evaluated for immunogenicity in mice. Cultural conditions necessary for maximum expression of the antigens were also defined. Actively growing "S. aureus" Smith strain culture was used to challenge lactating GF-1 strain mice which had been vaccinated with various capsule antigen …
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Glycerol permeability in two species of Peromyscus
… differences among separate populations of deer mice (Hunter, personal communication). Such findings prompted the present study of the permeability of red cells to glycerol in two different populations of the pinyon mouse (P. truei). In addition to this population comparison, the glycerol …
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Glycerol permeability in erythrocytes of Peromyscus californicus : the effect of temperature
The present work was done to determine the effect of temperature of the half-saturation constant (ø) and the maximum transport rate (K) of the facilitated diffusion of glycerol across the erythrocyte membrane of Peromyscus californicus.
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Specific connectivity and molecular diversity of mouse rubrospinal neurons
While much progress has been made in understanding the development, differentiation, and organization of the spinal motor system, the complex circuitry that is integrated to determine a motor behavior has yet to be fully understood. The activity of motor neurons is influenced by sensory feedback, …
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PITUITARY-THYROID FUNCTION IN THE C57 BL/KSJ DB/DB DIABETIC MOUSE.
… to a reduction in T3 receptor binding. Diabetic mice have subnormal serum T4 concentrations and supranormal T3 concentrations which are most pronounced between 8 and 10 weeks of age. Thyroid glands of diabetic animals appear hypoactive histologically. Serum TSH concentrations approximate those …
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Part I characterization of MyoR in C2C12 mouse fibroblasts. Part II isolation and characterization of a novel class II bHLH transcription factor from the black widow spider, latrodectus hesperus
<p>PART I</p> <p>The basic helix-loop-helix (bHLH) family of transcription factors are involved in a variety of developmental processes. MyoR is the mouse homologue of the human transcription factor ABF-1 . MyoR is classified as a class II basic-helix-loop-helix transcription factor. In order to …
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Representations and Transformations of Odor Information in the Mouse Olfactory System
… kind of olfactory receptor (M71). In these mice, there is a 1,000-fold increase in sensory neurons expressing the M71 receptor ligand acetophenone, and a 20-fold reduction in neurons expressing olfactory receptors from the endogenous repertoire. These M71 transgenic mice provide a useful …
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Physiology and Pathophysiology of Retinoid and Lipid Storage in Mouse Hepatic Stellate Cell Lipid Droplets
… store retinyl ester in lipid droplets, LRAT KO mice are not more susceptible than WT to the development of diet- or chemically-induced hepatic fibrosis. We found that, while the culture of HSCs on plastic results in the typical hallmark events of HSC activation, including the upregulation of …
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The effects of calorie restriction and aging on natural killer cells in c57bl/6 mice
… in aged (22 mo) calorie restricted (CR) C57Bl/6 mice. NK cells are innate immune cells capable of killing tumor or virus-infected cells. We used flow cytometry to analyze NK cell maturation in young ad libitum (AL) fed, young CR, aged AL, and aged CR mice. Aged CR mice had significantly reduced …
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Molecular and Physiological Adaptations to Weight Perturbation in Mice
… adiposity sufficient to derange metabolic physiology in a manner that negatively impacts the health of the individual. While population-based cut points based on body mass index (BMI) are frequently used as a means of identifying such individuals, this is an imprecise approach since the …