Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"MiR-184"”.
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Elucidation of the Role of miR-184 in the Development and Maintenance of the Drosophila Melanogaster Nervous System
MicroRNAs (miRNAs) are short, non-coding RNA sequences that are generated from longer primary transcripts (pri-miRNA). These pri-miRNAs are processed by the endonuclease Drosha into a hairpin secondary structure (pre-miRNA), exported from the nucleus and cleaved by the enzyme Dicer to form a duplex …
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MicroRNA-184: A Multifaceted Regulator of Epidermal Keratinocyte Biology
… (~22 nt) genetic molecules called microRNAs (miRNA) that regulate gene expression by repressing messenger RNA (mRNA) have gained attention as robust regulators of keratinocyte biology and key players in psoriasis. A specific miRNA elevated in psoriasis, miR-184, modulates the expression of …
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Identification and Characterization of Sex-Specific Transcripts in the Blood-Brain Barrier of Drosophila melanogaster
… their possible targets. I explored a role for miR-184, the most abundant miRNA in the bbb of Drosophila in male courtship. Alterations of the miR-184 levels in the adult bbb resulted in significant reduction in courtship suggesting its importance for normal male courtship in the bbb. …
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Evaluation of small extracellular vesicular microRNAs as biomarkersfor exposure of nicotine and E-liquids on human lung cells
… health effects. In this study, we explored miRNAs from small extracellular vesicles (sEVs) for nicotine and E-liquid-associated biomarkers. We investigated miRNAs using NGS and further focused on a large miRNA cluster on C14q32 (C14MC), known to be dysregulated in lung-associated diseases. …
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The role of small RNAs in caste determination and differentiation in the bumble bee, Bombus terrestris
… of the role of gene regulation by microRNAs (miRNAs), non-coding RNA molecules that regulate development in animals and plants. In this thesis I therefore investigated the role of miRNAs in caste determination and differentiation in the bumble bee Bombus terrestris. In Chapter 2, I used deep …