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Showing 1 to 2 of 2 for “"Mex3"”.
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Investigating Adult Stem Cell Lineage Specification in the Freshwater Flatworm Schmidtea mediterranea
… RNAi functional analysis, I have identified a MEX3 homolog (Smed-mex3-1) and a putative MYB-type transcription factor (Smed-myb-1) as regulators of ASC differentiation. This body of work demonstrates that (A) mex3-1 is a critical factor broadly required for ASC differentiation, and (B) myb-1 is …
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Structural and Biochemical Investigation of the Pan2-Pan3 Deadenylase Complex
Almost all mature eukaryotic mRNAs contain a 3′ polyadenosine (poly(A)) tail, which promotes nuclear export of mRNAs, protects transcripts from exonucleolytic decay, and increases translation efficiency. As the poly(A) tail is involved in many steps of gene expression, its length is highly …