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Showing 1 to 2 of 2 for “"Metnase"”.

  1. DNA repair proteins Metnase and PARP1 regulate DNA integration

    Nie, Jingyi, author, Nickoloff, Jac A., advisor, Bailey, Susan M., committee member, Liber, Howard L., committee member, Chen, Chaoping, committee memberColorado State University. Libraries2015

    … repair pathways often engage in DNA integration. Metnase is a fusion protein that only expresses in higher primates, including humans. Metnase contains a SET methyltransferase domain and a transposase domain. Metnase promotes efficiency and accuracy of NHEJ and promotes DNA integration. The SET …

    colostate Repository record

  2. ARTEMIS AND METNASE MEDIATED PROCESSING OF 3΄-BLOCKED DNA LESIONS: ROLE IN RADIO/CHEMORESISTANCE AND DNA REPAIR

    Mohapatra, Susovan2017

    … recently discovered, DNA end-specific nuclease, Metnase is a candidate enzyme for repair of such breaks. To study the role of Metnase in resolution of 3ʹ-blocked termini, several substrates mimicking such breaks were constructed. A 3ʹ-phosphoglycolate moiety on longer overhangs (4 and 6 bases) …

    vcu Repository record