Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 143 for “"Methamphetamine"”.
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Treatment During Abstinence from Methamphetamine in a Rat Model of Methamphetamine Use Disorder
Methamphetamine (METH) is a psychostimulant with high abuse potential. Currently there are no pharmacological treatments specific for relapse to METH use disorder. Chronic METH abuse has been associated with changes to the dopamine and glutamate neurotransmitter systems, as well as inflammation. …
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Executive functioning in methamphetamine psychosis
An association between methamphetamine dependence and neurocognitive impairment has long been established. However, there are a number of research gaps. First, while evidence suggests that the primary cognitive domains affected in methamphetamine dependence are executive functions; previous …
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Pharmacological management of acute methamphetamine withdrawal
People who cease regular methamphetamine (MA) use can experience a distinct withdrawal syndrome, that when untreated forms a significant barrier to people meeting their treatment goals. There are no effective pharmacological treatments for MA withdrawal. The aim of this thesis is to improve our …
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Methamphetamine: Airborne analysis and oxidative destruction
… aspects of the remediation of former clandestine methamphetamine laboratories: developing methods for detecting airborne methamphetamine with short (ca. 20 min) sampling times, and oxidation of methamphetamine as a possible decontamination method. Dynamic solid phase microextraction (SPME) had …
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Gabab Regulation of Methamphetamine-Induced Associative Learning
… there are no FDA-approved pharmacotherapies for methamphetamine (Meth) addition. There is an immense need to identify the neurobiological underpinnings of psychostimulant addiction and develop efficacious drug therapies to compliment the current mainstay treatment of behavioral/cognitive …
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Neurodegeneration and behavior in rodents treated with chronic methamphetamine
… people over the age of twelve reported using methamphetamine (meth) that same year. Meth is a powerful psychostimulant with a high propensity for abuse. The number of people using meth has been steadily increasing over the past decade alongside increases in meth-related hospitalizations, …
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Methamphetamine, interleukin-6 and perineuronal nets in synaptic plasticity
… This study evaluated the effect of modulating methamphetamine (METH) action on learning and memory, the effect of METH-induced metabolites on neuronal structure and the biochemical and structural analysis of the lecticans and hyaluronan (HA) in perineuronal nets (PNNs), which are essential …
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EMPLOYED VS UNEMPLOYED METHAMPHETAMINE USERS: SPECIFIC IMPLICATIONS FOR CASE MANAGERS
… the past two decades the abuse and dependence of methamphetamine has increased and the rates have remained steady (Substance Abuse and Mental Health Services Administration, 2004). Advances have been made in the development of treatments for substance abuse and dependence. Research has continued …
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Methamphetamine use and HIV risk among severely mentally ill inpatients
… factor for sexual risk behaviours. Worldwide methamphetamines are the most commonly used illicit stimulant. Both injectable and noninjectable methamphetamines have evidenced associations with high risk sexual behaviours. Smoking and inhalation of crystal methamphetamine is the predominant mode …
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Relationship between white matter changes and aggression in methamphetamine dependence
Background: Methamphetamine (MA) abuse is a growing problem in the world and especially in South Africa’s Western Cape. Amphetamine-type stimulants have become the second most widely abused illicit drugs worldwide. Admission data from substance abuse treatment centres in the Western Cape show the …
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The societal costs of methamphetamine use in Western Cape Province
Methamphetamine (meth) use results in various costs accruing to the meth user, society, and government. Internal and external costs of the pandemic are widespread, affecting the healthcare and social welfare systems, policing, private security, and the judicial and corrective services system. This …
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Prenatal Intravenous Nicotine Exposure: Increased Motivation For Methamphetamine Self-Administration, Altered Methamphetamine-Induced Locomotor Activity and Brain-Derived Neurotrophic Factor Protein Levels In Adult Rats
… aversive effects of the highly addictive drug methamphetamine (METH). Specifically, the experiment investigated the impact of US-preexposures on METH-induced CTA, in periadolescent (PND 30 - 40) and young adult (PND 60 - 70) rats with two preexposure-to-conditioning delays; either 3 or 9 days. …
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Correlation study of methamphetamine abuse and resultant levels of child neglect
… of child neglect and proportionate levels of methamphetamine abuse. The term abuse will be used to refer to the chronic, compulsive use of methamphetamine in such a manner, that it will assume a central and negative role in the individual's life style and will result in impaired functioning …
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Methamphetamine and amphetamine differentially affect associative learning: behavioral and neurobiological correlates
… in the effects of two psychostimulants; methamphetamine (METH) and amphetamine (AMPH). These drugs were chosen because, while structurally very similar, they have differing abuse liabilities. Some of the disparities in rates of use and abuse can be accounted for by availability, with METH …
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Investigating the Influence of Methamphetamine on brain metabolism using 1H-MRS
Methamphetamine (MA) has been shown to have a detrimental relationship with on neuronal integrity and viability, and has been associated with decreased executive function. The association of acute and short-term MA abstinence on brain metabolism, in adult MA abusers, is understudied. Negative …
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White matter correlates of neuropsychological function in young adult methamphetamine users
Background: Methamphetamine (MA) abuse is a global health concern due to widespread use and harmful effects, which includes neurotoxicity. This study aimed to describe neurocognitive deficits associated with MA dependence in young adults and to explore whether these deficits correlate with white …
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Practice Considerations For The Anesthesia Practitioner For Methamphetamine Substance Use Disorder Patients
… to impact families and communities throughout. Methamphetamine accounts for approximately 1.6 million individuals. It is important for anesthesia providers to be aware of the potentially lethal effects if patients undergoing anesthesia are using methamphetamine. The consequences of which may …
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School learner's perceptions of the factors that influence methamphetamine use in Manenberg
… perceptions of the factors that influence methamphetamine use in Manenberg. To meet this aim, three objectives were proposed namely, to explore school learners' knowledge and understandings of methamphetamine use; to explore school learners' perceptions of methamphetamine and its uses and; …
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