Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 54 for “"Methadone"”.
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Methadone maintenance : treatment as social control
Thesis. 1976. M.C.P.--Massachusetts Institute of Technology. Dept. of Urban Studies and Planning.
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Methadone metabolism in placentas from preterm pregnancies
… system responsible for the N-demethylation of methadone in human preterm placentas. The metabolism of methadone revealed typical Michaelis-Menten saturation kinetics. Methadone was N-demethylated to EDDP, only, by human placental aromatase. This was confirmed through the use of chemical …
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An exploratory study of heroin addicts' perceptions of methadone treatment
Methadone treatment continues to be the most widely used treatment modality for heroin addiction despite continued controversy. The efficacy of methadone treatment has been determined primarily by statistical research of program outcomes. This study explored heroin addicts' perceptions of methadone …
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Acute pain management in methadone maintenance treatment / by Mark Doverty.
… help direct optimal acute pain management for methadone maintenance patients.
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A Study of the Personality Characteristics of Patients in Methadone Maintenance Programs
Estimates of the number of heroin addicts in the United States vary between 200,000 and 500,000. Although differences of opinion exist as to the numbers of heroin addicts, there is little argument about the cost of supporting their addiction. Hundreds of millions of dollars are lost each year …
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An Evaluation of Mental Health and Methadone: Anxiety, Depression, and Drug Use
<p>As a part of the Masters of Science in Behavioral Health field placement, an evaluation was conducted of the integrated treatment plan in mental health and substance abuse at Bay Area Addiction Research and Treatment (BAART) programs. The goal of the BAART programs are to provide comprehensive …
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Patient participation, encounter, and methadone-reinforcement in the treatment of heroin addicts
… inpatient programs for heroin addicts undergoing methadone maintenance and drug abusers. These facets included the investigation and evaluation of (a) motivational factors; affecting the voluntary participation of inpatient heroin addicts and drug abusers in behavioral and pharmacological therapy, …
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Buprenorphine and Methadone in pregnancy: effects on the mother, fetus and neonate.
… Neonatal Abstinence Syndrome (NAS) compared to methadone maintenance and non-opioid exposed control pregnancies. This is the first study to present results comparing the two treatment groups to a control population. The trial was a prospective, non-randomised, open-label, flexible dosing study …
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Neuropsychological function as a result of chronic exposure to methadone and other opioids
… users (illicit heroin users, patients prescribed methadone for illicit opioid dependence and patients taking opioids as part of the management of chronic pain) have identified performance deficits in measures of executive functioning and memory. These have included impairments within the domains …
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Methadone maintenance : a program-evaluation study of a private clinic at Windsor Western Hospital Centre.
Paper copy at Leddy Library: Theses & Major Papers - Basement, West Bldg. / Call Number: Thesis1974 .G72. Source: Masters Abstracts International, Volume: 40-07, page: . Thesis (M.S.W.)--University of Windsor (Canada), 1974.
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Experiences and satisfaction with methadone maintenance treatment (MMT) health services: views from a small Ontario city
… health issue affecting thousands of Canadians. Methadone Maintenance Treatment (MMT) is considered the gold standard in Canada, and the world, for treating opiate dependence. In the past, Canadian research into opiate addiction and the effectiveness of MMT has mostly focused on larger cities: …
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Exploring the role of mu opioid receptor (OPRM1) and CYP2B6 gene variations for methadone pharmacogenomics. Can these variations be used to advance toxicological interpretation post-mortem?.
Methadone is increasingly involved in drug overdose cases and the molecular actions of the drug in vivo are largely unknown requiring elucidation. This study set out to examine the relationship between methadone toxicity and CYP2B6 and mu (μ) opioid receptor (OPRM1) single nucleotide polymorphisms …
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The Effects of Maternal Administration of Methadone on Beta-endorphin Content in the Brain and Pituitary of the Rat Progeny
<p>Methadone is often used in the maintenance and detoxification of opioid-dependent pregnant women. This use of methadone during pregnancy is known to be associated with teratogenic effects observed in the progeny. The present study is an attempt to gain insight into possible pathophysiologic …
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Heroin detoxification during pregnancy: a systematic review and retrospective study of management of heroin addiction in pregnancy
There is a general consensus that methadone maintenance is the gold standard in the management of pregnant heroin users. However, in South African state hospitals, methadone withdrawal is the routine procedure offered to these patients, as methadone maintenance programmes are unavailable in the …
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Heroin and methadone substitution treatments : harm reduction and the effectiveness of 'flexible' prescribing for the treatment of opioid dependency
In the mid 1990's the UK government began to focus on problem heroin use mainly as a drug related crime issue, and so attracting and retaining clients became a treatment priority. The concept of flexible prescribing, matching individual clients to treatment programmes appropriate to their drug …
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"I Was Not Sick and I Didn't Need to Recover": Methadone Maintenance Treatment (MMT) as a Refuge from Criminalization
<p>Methadone Maintenance Treatment (MMT) has been undergoing a cultural and epistemological shift away from an approach that emphasized client stabilization and a reduction of social harms towards one grounded in values associated with the recovery movement. These changes include promoting a view …
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Long term outcomes of methadone substitution therapy (OST-M) for opiate dependency: the effect of patient characteristics and co-morbidities
… last 30 years. Opioid substitution therapy using methadone (OST-M) is an effective treatment for opioid dependency. Though the effectiveness of OST-M in delivering harm-reduction is well evidenced, evidence demonstrating recovery is limited as is understanding of those factors influencing …
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Therapy development of group contingency management in methadone treatment: Pilot 1 - the application of a percentile schedule to enhance attendance behaviors and cocaine abstinence
… cocaine abstinence among cocaine abusing methadone-maintained participants having initial low rates of cocaine abstinence. In a multiple baseline across behaviors with reversals design, the procedure was applied to four target behaviors in sequence: incentive group attendance, urinalysis …
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Characterizing Effects of Sphingosine-1-Phosphate Receptor 1 Activation in Subtypes of Central Amygdala Neurons and Effects of Prenatal Methadone Exposure on Motor Cortex Neurons in Mice
… motor cortex neurons in mice exposed to prenatal methadone. Methadone is a synthetic μ-opioid agonist used for opioid maintenance therapy and chronic pain management. Methadone treatment for opioid use disorder in pregnant women can result in structural changes within the brain of their offspring …
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