Global ETD Search
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Showing 1 to 2 of 2 for “"Metastatic dormancy"”.
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Inflammation triggers Zeb1-dependent escape from tumor dormancy
… and can create a favorable environment for metastatic outgrowth. I evaluated whether lipopolysaccharide (LPS) could induce an inflammatory response, leading to the activation of the cell-biological epithelial-mesenchymal transition (EMT) program in dormant disseminated cancer cells in vivo, …
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Metastatic Reactivation and Progression Result From Fak-Mediated Disruption of Innate Immune Signaling
<p>Metastatic relapse may arise from disseminated tumor cells (DTCs) that undergo a period of dormancy before reactivating and progressing to life-threatening disease. How cancer cells evade ensuing immune surveillance upon reactivation is poorly understood, but critical for the development of …