Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Metastasis Suppression"”.
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Post-Translational Regulation of Zeb1 Contributes to Tgfβ-Mediated Emt
… Understanding the process which contributes to metastasis provides promise for the discovery of novel therapeutic targets. Epithelial-to-mesenchymal transition (EMT) is a proposed model for the initiation of metastasis. During EMT epithelial cells lose their cell adhesion properties and acquire …
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The role of kisspeptin and its cognate receptor GPR54 in normal and abnormal placentation
… receptor GPR-54 originally involved in tumour metastasis suppression and regulation of puberty, have been implicated in the inhibition of trophoblast invasion. Expression levels of kisspeptin and its receptor in trophoblast cells are highest in the first trimester, when control of trophoblast …
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Targeting the Urokinase Plasminogen Activator System Combined with Chemotherapy-a Potentially Novel Therapeutic Approach for Pancreatic Cancer
… with Gemcitabine resulted in tumour growth and metastasis suppression, likely through inhibition of cancer cell proliferation, extracellular matrix degradation, and epithelial-mesenchymal transition (EMT). The combination treatment notably suppressed cancer stemness, a key factor in tumour …