Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"Metastable proteins"”.
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Homeostasis of metastable proteins in Alzheimer's disease
… misfolding and aggregation of a specific set of proteins, including amyloid plaques and neurofibrillary tangles in AD. One promising avenue for progress in the field is to improve our understanding of the mechanisms by which cellular dysfunction arises from the initial protein aggregation events. …
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Investigating the protein disaggregation machinery in the early secretory pathway
… responsible for managing aggregation-prone proteins. Recent findings from our laboratory have illuminated the inherent capability of the early secretory pathway, specifically the endoplasmic reticulum (ER), in resolving preformed protein aggregates, particularly under conditions of …