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Showing 1 to 20 of 1068 for “"Metabolite"”.
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Metabolite identification using infrared ion spectroscopy
Contains fulltext : 286937.pdf (Publisher’s version ) (Open Access)
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Quantitative trait loci (QTL) for metabolite accumulation and metabolic regulation : metabolite profiling of interspecific crosses of tomato
… tissues can be efficiently assessed by metabolite profiling techniques, which allow the multivariate detection of metabolites of a given biological sample. Here, a GC/MS metabolite profiling approach has been applied to investigate natural variation of tomatoes with respect to the …
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Understanding Control of Metabolite Dynamics and Heterogeneity
… for microbes, and cause changes in intracellular metabolite levels. Microbial response to dynamic environments requires coordination of multiple levels of cellular machinery including gene expression and metabolite concentrations. This coordination is achieved through metabolic control systems, …
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Synthetic Studies towards Opaliferin, a Tetracyclic Polyketide Metabolite
Opaliferin (12) was originally isolated and characterised from an entomopathogenic fungus of Cordyceps sp. NBRC 106954 by the Grudniewska group in 2014. The fungus Cordyceps sp. is a single ascospore isolated from a fruiting body found on the larvae of Meimuna opalifera also known as Walker’s …
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An electrochemical pipette for the study of drug metabolite
… offers an effective means of mimicking enzymatic metabolite pathways, particularly the oxidative pathways catalyzed by the cytochrome P450 superfamily. The electrochemical generation and identification of metabolites are time-sensitive, necessitating adjustable cell designs for accurate …
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Metabolite biosynthetic enzymes: catalysis, substrate specificity and protein engineering
… important part of how bacteria survive, primary metabolites are involved in growth and development while secondary metabolites can function as signaling molecules, scavengers or chemical weapons. These small molecules have a myriad of diverse chemical structures that grant them biomedical …
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Metabolite Profiling: Correlates and Associations with Incident Cardiovascular Outcomes
… of common CVD related factors (CVRFs) with metabolite profiling and the associations of metabolite profiling with CVD outcomes. I first conducted a comprehensive review of the published literature on the topic to provide background. Next, I conducted cross-sectional analyses assessing the …
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Metabolite profiling of Eragrostis nindensis during desiccation and recovery
… biochemical processes including accumulation of metabolites that shield the plant cells from photo-oxidative damage and reactive oxygen species. A global understanding of the whole plant using a multi-omics approach will provide more insights into how different parts of the plant deal with …
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The Integration of Metabolite and Hormone Signalling Drives Seedling Development
Sugars have a profound impact on plant biology, acting as structural components, signalling molecules, and sources of energy. As such, the availability of sugars has important implications for plant growth and development. Sugar levels rise and fall as part of a daily cycle, while cues from other …
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Etablierung von Methoden zur Bioevaluation antitumoraler Naturstoffe, Metabolite und Analoga
Die Ziele, die ich mir vor Beginn meiner Arbeit gesteckt habe (siehe 1.3), wurden weitestgehend erreicht. Es wurde ein Verfahren entwickelt, mit dessen Hilfe Illudin M 11 zuverlässig gewonnen werden kann. Die Aufzucht von O. olearius im Medium HA- und die Extraktion nach Kutscher-Steudel erwiesen …
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Microbial Metabolite Regulation of Microglial AHR Signaling in Alzheimer’s Disease
… factors, particularly the gut microbiota and its metabolites, play a significant role in shaping brain immune responses, including microglial activation. However, the mechanisms linking gut dysbiosis to microglial dysfunction in AD are poorly understood. The aryl hydrocarbon receptor (AHR), a …
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Development Of Isotags For Nmr Based Metabolite Profiling And Applications
… tool for both qualitative and quantitative metabolite profiling analysis. However, accurate quantitative analysis of biological systems especially using one dimensional NMR has been challenging due to signal overlap. In contrast, the enhanced resolution and sensitivity offered by …
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Metabolite Production in Callus Culture of Burdock (Arctium lappa L.)
… usage, and analyze these potential medicinal metabolites. The metabolites in burdock we were most interested in were phenolic compounds because of their high content in burdock and their well-known antioxidant bioactivities and related properties which are likely to be useful for treating …
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Octacalcium Phosphate - Metabolite Composites: model compounds for bone mineral structure
… a hypothesis has been proposed: that other metabolites similar to citrate can be incorporated into the mineral structure, and differences in metabolite incorporation cause fundamental differences in the physical properties of bone mineral. Thus understanding the effect of metabolite …
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Machine Learning Methods for Discovering Metabolite Structures from Mass Spectra
Small molecule metabolites mediate myriad biological and environmental phenomena across host-microbiome interactions, plant chemistry, cancer biology, and various other processes. Mass spectrometry is often used as an analytical technique to investigate the small molecules present in a sample, …
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Plasma amino acid and metabolite changes in pigs during endotoxemia
… (N = 9, 26.9 ± 1.07 kg BW) on plasma AA and metabolite levels in pigs. Data were used to generate prediction equations establishing mathematical relationships between plasma AA levels and numerous blood metabolites (e.g., total lipid, LDL, HDL, blood urea nitrogen, etc). These equations have …
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Computational Analysis of LC-MS/MS Data for Metabolite Identification
… aims at the detection and quantitation of metabolites within a biological system. As the most direct representation of phenotypic changes, metabolomics is an important component in system biology research. Recent development on high-resolution, high-accuracy mass spectrometers enables the …
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The Role of the Alternaria Secondary Metabolite Alternariol in Inflammation
… was to assess the role of Alternaria secondary metabolites that are synthesized by genes called polyketide synthases (PKS) in immune responses of lung epithelial cells.
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Advance metabolite identification from tandem mass spectra using deep generative models
… (MS/MS) is a modern technique for measuring metabolites. MS/MS spectra represent molecules by the fragment patterns of compounds that contain structural features of the precursor molecules. The database-searching strategy is the most popular for metabolite identification among its peers. It …
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