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Showing 1 to 20 of 37 for “"Metabolic studies"”.

  1. Metabolic studies in acute insulin deficiency

    Stern, Milton1962

    This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).

    iupui Repository record

  2. Structural and Metabolic Studies of Sphingolipids

    Hirschberg, Carlos BenjaminUniversity of Illinois at Urbana-Champaign2014

    Made available in DSpace on 2014-12-10T23:01:00Z (GMT). No. of bitstreams: 1 7114795.pdf: 6880498 bytes, checksum: 6ad7196cbbcd286054169ee060d9ca04 (MD5) Previous issue date: 1970

    uiuc Repository record

  3. Kinetic and metabolic studies in HPRT deficiency

    Steyn, Lafras MaraisDivision of Chemical Pathology1983

    … 550μU/mg Hb (reference range 1680-2480μU/mg Hb). Studies to determine whether the low hypoxanthine-guanine phosphoribosyltransferase activity was caused by an altered Kₘ of the enzyme for one of its substrates, showed that there was substrate inhibition of the enzyme activity by hypoxanthine. This …

    cape-town Repository record

  4. Analytical and metabolic studies of the trypanocidal diamidines

    Atsriku, ChristianUniversity of Strathclyde2002

    … were no obvious qualitative differences in the metabolic profiles of pentamidine in either of the animals, the rate of metabolism in rats appeared to be faster. Pretreatment of rats with either 3-methylcholanthrene (3-MC), phenobarbitone (PB) or deltamethrin (DM) caused inhibition of pentamidine …

    strathclyde Repository record

  5. Synthetic and metabolic studies on centrally acting amines

    Zhao, ZhiyangVirginia Tech1991

    This dissertation is concerned with the metabolic bioactivation of several amines which are either known or suspected to be neurotoxic and with the exploration of bioactivation processes in order to generate metabolites with therapeutic potential. The following three programs were pursued in this …

    vt Repository record

  6. Metabolic Studies on the Cryptorchid Testis of the Rat

    Hollinger, Mannfred A.2016

    loyola-thes Repository record

  7. Metabolic studies on the nitrophile yeast Rhodotorula glutinis DSBCA06

    CIVIERO, ENRICOUniversità degli Studi di Cagliari2016

    … that we called DSBCA06. We examined the main metabolic features of the strain, also to determine the best growing conditions. At the same time, the ability of the strain to grow in presence of high nitrite concentrations was assayed, being a relevant feature poorly studied earlierfor other …

    cagliari Repository record

  8. Structural and Metabolic Studies of Glycosaminoglycans (Sulfatase, Hydrazine, Mucopolysaccharidosis)

    Shaklee, Patrick NeilUniversity of Illinois at Urbana-Champaign2014

    … cleavage of the polymer at pH 4.0. Initial studies with heparin-derived model compounds indicated that ester and N-sulfate substituents were stable during N(,2)H(,4) treatment but that uronic acids were converted to hydrazides which were epimerized at C-5 during the hydrazinolysis reaction. …

    uiuc Repository record

  9. Metabolic studies of mammalian cells in a fluidized bed reactor

    Schuppenhauer, Michael RainerETH Zürich1995

    ethz Repository record

  10. Biomimetic emulators of high potential peroxygenases: Implications in bioremediation and metabolic studies

    COCCO, GIANMARCOUniversità degli Studi di Cagliari2016

    Nowadays, classical (bio)remediation processes are affected by some economical and environmental drawbacks. These approaches often seem to be inadequate, particularly in the perspective of sustainable green processes. Since immobilized metalloporphines can emulate the active site of peroxidases and …

    cagliari Repository record

  11. Metabolic Studies on 1-Cyclopropyl-4-phenyl-1,2,3,6-tetrahydropyridinyl Derivatives by HPLC and LC-ESI/MS

    Shang, XueqinVirginia Tech1999

    The MAO-B catalyzed metabolic bioactivation of the parkinsonian inducing agent 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) to generate the neurotoxic 1-methyl-4-phenylpyridinium species (MPP+) is well documented. The N-cyclopropyl analog (CPTP) of MPTP is a mechanism based inactivator of …

    vt Repository record

  12. Clinical and metabolic studies with uricosuric agents in gout : a therapeutic assessment of Benemid and an experimental account of Tromexan.

    Sougin-Mibashan, ReubenGout1954

    cape-town Repository record

  13. Synthetic and metabolic studies on 1-methyl-4-(1-methylpyrrol-2-yl)-1,2,3,6-tetrahydropyridine, a neurotoxic analog of the Parkinsonian inducing agent MPTP

    Bai, HongVirginia Tech1991

    … ethylpyrrol-2-yl)-1,2,3,6-tetrahydropyridine. The metabolic studies of TMMP and MMDP+ were conducted with an HPLC diode array assay. Both in-vivo and in-vitro metabolic studies showed that TMMP is oxidized to its dihydropyridinium species (MMDP+) in a reaction catalyzed by MAO-B. MMDP+ undergoes …

    vt Repository record

  14. A subspace approach to high-resolution magnetic resonance spectroscopic imaging

    Lam, FanUniversity of Illinois at Urbana-Champaign2015

    … been recognized as a powerful tool for in vivo metabolic studies. However, research and clinical applications of in vivo MRSI have been progressing more slowly than expected. The main reasons for this situation are the problems of long data acquisition time, poor spatial resolution and low …

    uiuc Repository record

  15. Selective functionalization of azines via phosphonium salts

    Koniarczyk, J. Luke, author, McNally, Andrew, advisor, Chen, Eugene, committee member, Barisas, George, committee member, Chatterjee, Delphi, committee memberColorado State University. Libraries2020

    … and tritium is installed as a radiolabel for metabolic studies in the pharmaceutical industry. The protocol of the reaction is simple, and it functions on a wide range of building blocks and complex molecules. Additionally, the tritiation protocol was effectively applied on a selection of drug …

    colostate Repository record

  16. Biomimetic design for an under-actuated leg exoskeleton for load-carrying augmentation

    Walsh, Conor JamesMassachusetts Institute of Technology2006

    Metabolic studies have shown that there is a metabolic cost associated with carrying a load (Griffin et al, 2003). Further studies have shown that by applying forward propulsive forces a person can walk with a reduced metabolic rate (Farley & McMahon, 1992 and Gottschall & Kram, 2003). Previous …

    mit Repository record

  17. Diurnal and daily variation in creatinine excretion among preadolescent girls consuming three levels of dietary protein

    Donald, Patillo ElizabethVirginia Polytechnic Institute and State University1973

    … as a reliable index of protein nutriture in metabolic studies. The apparent contribution of lean body mass to creatinine excretion points to the need for experimental diets which are controlled for preformed creatine and creatinine in order to gain a greater understanding of the true effect …

    vt Repository record

  18. Interaction of phthalazines with molybdenum hydroxylases. Phthalazine and its 1-substituted derivatives as substrates, inhibitors and inducers of aldehyde oxidase and xanthine oxidase, both in vitro and in vivo.

    Johnson, ChristineUniversity of Bradford2009

    … been investigated both in vivo and /Ok in vitro. Metabolic studies, carried out by treating rabbits with both cold and 14C-labelled phthalazine, have shown that this compound is extensively metabolised in vivo, the major metabolite being a glucuronide conjugate. Very little unchanged phthalazine …

    bradford Repository record

  19. Integrative Multivariate Analysis of Mouse Liver Acini

    Cornelius, MercedesUniversity of Cambridge2024

    … patterns and the spatial separation of metabolic functions, recognized as liver zonation. The factors that govern this spatial phenotypic heterogeneity remain inadequately understood and hepatic pathologies persist as major contributors to global mortality rates. This research aimed to …

    cambridge Repository record

  20. Synthesis of Mycobacterial Ergothioneine biosynthetic pathway metabolites

    Khonde,Lutete PeguyDepartment of Chemistry2013

    … internal standards and probes for ergothioneine metabolic studies. Enantioselective sulfoxidation of EgtE enzyme substrate precursor, hercynyl cysteine sulfide gave the required hercynyl cysteine sulfoxide derivative and in same cases the hercynyl cysteine sulfone. Crude enzyme mediated …

    cape-town Repository record

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