Global ETD Search
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Showing 1 to 7 of 7 for “"Metabolic Control Analysis"”.
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Metabolic Control Analysis of Carbon Pathways
In a complex metabolic system, collective behaviors can emerge which are not obvious consequences of the individual components, because each of the components interacts with others in unpredictable ways. In the particular case of carbon metabolism, the emergent condition of this complex interaction …
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Reconstruction of metabolic pathways by the exploration of gene expression data with factor analysis
… linkages between genes within a single metabolic pathway, or alternative pathway routes under different environmental conditions, or provide information leading to the identification of genes for selection in animal and plant genetic improvement programs or targets for drug therapy. Many …
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Metabolic Pathway Optimization with Data Driven Approaches
The flux control coefficient (FCC) is a sensitivity coefficient that measures the percent change in flux as a result of a given percentage change in the activity of the enzyme. The higher the FFC the more controlling the step. However, the value for a flux control coefficient for a specific enzyme …
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Computer modelling applied to the Calvin Cycle
… the photosynthetic Calvin cycle. A set of metabolic modelling software tools, "Scampi", constructed as part of this project is presented. A unique feature of Scampi is that it allows the user to make a particular model the subject of arbitrary algorithms. This provides a much greater …
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Enzymatic Production of Cellulosic Hydrogen by Cell-free Synthetic Pathway Biotransformation(SyPaB)
… of enzymatic reactions from four different metabolic pathways, e.g. glucan phosphorylation, pentose phosphate pathway, gluconeogenesis, and hydrogenase-catalyzed hydrogen production, so as to release 12 mol hydrogen per mol glucose equivalent. To ensure the artificial enzymatic pathway would …
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Systems biology approach to understanding the control of glucose metabolism in healthy and apoptotic neurons
… to neurodegeneration in the mature CNS. Metabolic disturbances have long been associated with apoptosis-inducing agents, however, the mechanism underlying such changes remains controversial. In this study, our hypotheses was that decreased ATP turnover may bring about other metabolic …
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Analysing concerted criteria for local dynamic properties of metabolic systems
Metabolic systems tend to exhibit steady states that can be measured in terms of their concentrations and fluxes. These measurements can be regarded as a phenotypic representation of all the complex interactions and regulatory mechanisms taking place in the underlying metabolic network. Such …