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Showing 1 to 20 of 20 for “"Mesothelial cells"”.
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Role of peritoneal mesothelial cells and the inflammatory response in peritoneal fibrosis
… coagulation, infiltration of inflammatory cells, cell proliferation, extracellular matrix (ECM) deposition and remodelling, often with overlap between phases. The unique feature of peritoneal repair is that both small and large peritoneal wounds heal in a similar time. The peritoneum is a …
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Induction of epithelial to mesenchymal transition in mesothelial cells by secreted factors from uterine epithelial cells
Made available in DSpace on 2012-05-22T00:30:00Z (GMT). No. of bitstreams: 2 Masoud_Farzaneh.pdf: 34313918 bytes, checksum: e99d6869329b04b746cc82321b8f70bc (MD5) license.txt: 4065 bytes, checksum: 032671e283e8d231a619ff8c90294786 (MD5)
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Untersuchungen zum c-met/HGF-System an humanen Mesothelzellen in vitro
… serosa. This paper investigated whether human mesothelial cells, in vitro, expressed the c-met receptor and their sensitivity to stimulation with recombinant HGF. RT-PCR and Western Blot was used to show c-met-receptor-expression of human mesothelial cells. It was shown that mesothelial cells …
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IMMUNOPROFILE IN EFFUSION CYTOLOGY
… the value of a panel of markers in identifying cells in canine and feline effusions. MATERIALS AND METHODS: Human, feline and canine mesothelial cells were isolated in culture. Western‐blot (WB) analysis was used to ascertain antibody cross‐reactivity for all the markers, with the exception of …
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Untersuchungen zur Wirkung des Hepatocyte Growth Factor (HGF) auf Humane Omentum Majus Zellen
… on the influence of HGF on cultured human mesothelial cells (HOMC), according to their expression of the c-met receptor, the secretion of the fibrinolytic enzyme t-PA (tissue-plasminogen-activator) and the secretion of the antifibrinolytic enzymes PAI-1 and PAI-2 …
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Antifibrinolytische Eigenschaften humaner Mesothelzellen in vitro in Interaktion mit isolierten neutrophilen Granulozyten
… the pro- and antifibrinolytic process are mesothelial cells, the biggest cell population intraabdominal. They produce the fibrinolytic enzyme t-PA (tissue plasminogen-activator) and its inhibitor PAI-1 (plasminogen-activator-inhibitor-1). Our investigations of cultured human mesothelial …
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Stromal interactions in pleural mesothelioma
… The remainder are largely comprised of stromal cells, the roles of which have been relatively neglected by existing studies. Of particular interest are the cancer-associated fibroblasts (CAF) whose interactions with cancer cells modulates the tumour microenvironment. The rarity of mesothelioma …
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The role of the tumor suppressor gene, NF2, in the development of malignant mesothelioma
… p53 function and cellular growth in "normal" mesothelial cells and in a mesothelioma cell culture model were assessed. Normal function of NF2 was restored by transfection of a wild-type NF2 construct in a mesothelioma cell culture model. Additionally, NF2 expression was reduced in "normal" …
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The role of the tumor suppressor gene, NF2, in the development of malignant mesothelioma
… p53 function and cellular growth in "normal" mesothelial cells and in a mesothelioma cell culture model were assessed. Normal function of NF2 was restored by transfection of a wild-type NF2 construct in a mesothelioma cell culture model. Additionally, NF2 expression was reduced in "normal" …
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Analysis of Mouse EKLF/KLF2 E9.5 Double Knockout: Yolk Sac Morphology and Embryonic Erythroid Maturation
… of primitive erythroid and endothelial cells of the vasculature. Using light and electron microscopy, the yolk sacs and dorsal aortae from EKLF/KLF2 double knockout (KO) E9.5 (embryonic day 9.5) were examined to determine whether these KLFs have compensatory functions in morphology of …
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Adjuvant methods to identify and type tumor cells in serous effusions
… diagnosed as suspicious or positive for MM cells using DNA-ICM, immunocytochemistry and AgNOR-analysis as adjuvant methods. We further investigated the detection of 9p21 deletions by chromosomal FISH. To test the utility of adjuvant methods to identify and type tumor cells in serous …
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Mechanisms of mesothelial tissue lubrication
… shear stress that could damage the delicate mesothelial cells covering the tissue surfaces. Normally, the pleural space, which is filled with fluid, is able to sustain continuous shear loading throughout its lifetime. To understand the mechanisms in preventing frictional damage on mesothelial …
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Functions of The Homeobox Gene Dlx4 In Controlling Inflammatory Signaling and Metastasis of Epithelial Ovarian Cancer
… a glycosaminoglycan that is expressed on mesothelial cells lining the peritoneal cavity and abdominal organs. Secondly, my studies have identified that DLX4 induces CD44 expression by activating the pro-inflammatory cytokine interleukin 1-beta (IL-1β) which in turn stimulates the nuclear …
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Clinical resistance to platinum chemotherapy in ovarian cancer
… cell gel electrophoresis (comet) assay. Tumour cells from resected tumours or tumour and mesothelial cells from ascites were obtained from chemonaïve patients and those relapsing after platinum-based therapy. The average percent decrease in tail moment at the peak of crosslinking was 61.1% …
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Mesothelial and Mural Cell Contribution to Vascular Development through PDGF Signaling
… of blood vessels from mesoderm precursor cells. Angiogenesis is the formation of new vessels from existing vessels. Both processes involve hematopoietic, endothelial, and mural cells for the formation of mature, stable vasculature. While hematopoietic and endothelial cell contributions and …
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Reduktion der intraperitonealen Adhäsion humaner Magenkarzinomzellen in Nacktmäusen
Objective: Adhesion of tumour cells to mesothelial cells or extracellular matrix components is a pivotal step in developing peritoneal dissemination after gastric cancer. As phospholipids were found to reduce adhesion formation, especially at sites of peritoneal lesions(1) we assessed the …
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The potential role of innate immunity in the pathogenesis of post-operative adhesions
… differentiation of several cell types including mesothelial cells, fibroblasts, and inflammatory and immune cells. Substances released from these cells regulate fibrinolytic activity, tissue remodeling, angiogenesis, and extracellular matrix turnover, processes that are known to be central to the …
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The Role of IGF-1 and Notch Signaling in Thoracic Malignancies.
… (small cell lung cancer, or SCLC) and mesothelial origin (malignant mesothelioma, or MM). The DNA oncogenic virus Simian Virus 40 (SV40) has been shown to cooperate with environmental oncogenic fibers in the onset of MM. Insulin like growth factor-1 (IGF-1) signaling plays a central …
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Zytologie und Immunozytochemie von Mesothelzellen im Ergüssen
Ziel der Arbeit war es, die Reaktionen des Mesothels in Ergußflüssigkeiten bei Entzündungen und malignen Erkrankungen zu untersuchen. Zur Verfügung standen 54 <br>Pleuraergüsse und 17 Aszites. Aus den Ergüssen wurden mit verschiedenen Techniken (Zytozentrifuge, Ausstriche, Adhäsionsobjektträger) …