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Showing 1 to 3 of 3 for “"Mesoscopic clusters"”.

  1. Polymorphism of Protein Condensates

    … into amyloid structures. Recently discovered mesoscopic protein-rich clusters may act as crucial precursors for the nucleation of ordered protein solids, such as crystals, sickle hemoglobin polymers, and amyloid fibrils. These clusters challenge settled paradigms of protein condensation as the …

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  2. Fragmentation of Charged Binary Clusters

    Fragmentation of binary mesoscopic clusters composed of H2O/CH3OH and charged with ions (Na+, K+, Cs+,F^, Cl-, I-) of similar sign are studied by molecular simulation. The fragmentation involves the departure of a cluster containing one or more ions from the parent droplet by a break-down of the …

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  3. Nonclassical Mechanisms to Inhibit β-Hematin Crystallization Illuminate the Cooperative Action of Antimalarials

    … longer described fully by classical step flow. Mesoscopic hematin-rich clusters contribute to both nucleation and crystal growth, revealing a nonclassical pathway that coexists with surface-mediated growth. On this basis, the dissertation develops a framework in which antimalarial inhibition may …

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