Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 14 of 14 for “"Mesoporous Silica Nanoparticles"”.
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Development of tandem catalytic systems utilizing mesoporous silica nanoparticles
… used to synthesize these molecules. Using mesoporous materials, mesoporous silica nanoparticles, specifically, as supports and compartmentalization tools in tandem catalysis can increase recyclability and durability, making an even more efficient and green catalytic system. MSN makes an …
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Formulation Devlopment Of Mesoporous Silica Nanoparticles As An Injectable Delivery System
… versatile and robust injectable carrier based on Mesoporous Silica Nanoparticles (MSN) for drug/drug combination therapies. The objective of my dissertation was to optimize surface functionality, particle shape and methods of colloidal stabilization of mesoporous silica by PEG for delivery of …
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Critical considerations in development of mesoporous silica nanoparticles for biological applications.
In the past ten years, mesoporous silica nanoparticles have been some of the hottest materials investigated for biomedical use. Mesoporous silica nanoparticles are size-controllable and discrete particles with high surface area, large pore volume, and easy surface modification properties. These …
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PREPARATION AND EVALUATION OF MESOPOROUS SILICA NANOPARTICLES FOR PLATINUM-ACRIDINE ANTICANCER DRUG DELIVERY
Mesoporous silica nanoparticles (MSNs) have a wide range of applications in the basic and biomedical sciences. Because of their unique pore structures and physicochemical properties, MSNs have recently attracted major attention as an inert carrier material in oncology drug formulations. In this …
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Light and nanoparticle-based approaches to the control of ion channels and drug delivery
… after internalization of bio-functionalized mesoporous silica nanoparticles loaded with cargo. We developed an improved synthesis method to optimize size control of mesoporous silica nanoparticles in the 20-200nm range while preserving porosity. We optimized surface bio-functionalization to …
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GROWTH OF SILICA-BASED NANOPARTICLES: CONTROLLING STRUCTURE AND FUNCTION
Silica chemistry provides a uniquely tunable platform for nanoparticle synthesis, where particle size, nanoscale morphology, and surface properties can be precisely controlled. Recent advances demonstrate that conveniently accessible parameters, including silica precursor chemistry, solvent, and …
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SYNTHESIS, SURFACE MODIFICATION, AND CHARACTERIZATION OF BIOCOMPATIBLE MULTIFUNCTIONAL NANOPARTICLES
… field. Recently, fluorescent and magnetic silica-based nanoparticles (NPs) have received much attention because of its biocompatible and engineerable-surface. Mesoporous silica nanoparticles first produced in 1990s become an alternative excellent candidate to load biomolecules, organic …
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NANOCOMPOSITES CONTAINING GOLD NANORODS FOR TWO-PHOTON IMAGING, PHOTODYNAMIC THERAPY AND DRUG DELIVERY
… nanocomposites, nanocomposites containing mesoporous silica and gold nanorod are considered as the most highly researched field owing to their novel properties of single-component structures. Gold nanorod is well-known for its large two-photon action cross section (10E4 GM), high two-photon …
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Inorganic nanoparticles for applications in biomedical sciences
… containing holmium-165 iron garnet (165HoIG) nanoparticles, which can be neutron activated to 166Ho and used for radiotherapy of SCC. The synthesis, characterization and stability of the bandage were also reported. Here, we tested the in vivo efficacy of the 166HoIG-PAN bandage for the …
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Nanotechnology-based strategies for periodontitis: nanoparticles as drug delivery systems and antimicrobial agents against biofilm formation
… Επίσης, τα μεσοπορώδη νανοσωματίδια πυριτίας (mesoporous silica nanoparticles - MSNs) διαθέτουν υψηλή ικανότητα φόρτωσης φαρμάκου και ρυθμιζόμενους ρυθμούς απελευθέρωσης, ενώ στα υβριδικά και στα συνθετικά συστήματα νανοσωματιδίων-υδρογέλης εκμεταλλεύεται η πολυλειτουργικότητα τους για να …
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Effect of Mesoporous Silica-Loaded Anticancer Drugs on 3D vs 2D Models of Colon Cancer Cells
… CRC. Both anticancer drugs were loaded onto mesoporous silica nanoparticles (MSNs) and tested on 3D spheroids and 2D monolayer cells of the HCT116 colon cancer cell line. Due to its poor water solubility, DMU121, a synthesised chalcone with potential anticancer properties, was encapsulated …
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Study of porous magnetic nanocomposites for bio-catalysis and drug delivery
… safe materials used in medicine are iron oxide nanoparticles. This project describes the development of several formulations based on magnetite nanoparticles for drug delivery applications. Utilising magnetic nanoparticles in drug delivery systems allowed for the synergistic effects of …
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Novel thin film nanocomposite membranes with improved properties for enhanced desalination performance
… polymeric membranes. However, the possibility of nanoparticles’ leakage and their low compatibility with organic membranes make the successful fabrication of TFN membranes challenging. Hence, investigating the structure-performance correlation of TFC/TFN membranes and their interactions with the …
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Harnessing the optical properties of gold nanorods: fluorescence enhancement, biosensing and photothermal therapy
… this thesis, including thiol functionalization, silica coating and layer-by-layer wrapping of polyelectrolytes. Methods for characterization of gold nanorods, and their surface coatings are described, and the chapter ends with a dissertation overview. Plasmonic nanoparticles can strongly interact …