Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 6 of 6 for “"Mesolimbic pathway"”.
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INVESTIGATING SEX DIFFERENCES IN THE TRANS-SYNAPTIC REGULATORS OF MESOLIMBIC DRIVEN PALATABLE FOOD INTAKE
… strategy to trace upstream afferents of the mesolimbic pathway in male and female rats. Surprisingly these experiments revealed different afferent pathways in male and female groups. Female afferents of the mesolimbic pathway were labeled: BNST VTA NAcSh, while male afferents labeled: LSN …
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THE ROLE OF DOPAMINE D3 RECEPTORS IN THE CONTROL OF ALCOHOL INTAKE
Background: Mesolimbic dopamine controls drug and alcohol seeking behavior. Stimulation of dopamine D3 autoreceptor reduces extracellular levels of dopamine. We tested the hypothesis that dopamine D3 receptor (D3R) gene deletion or its pharmacological blockade counteracts alcohol preference and …
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Stimolazione da etanolo del sistema dopaminergico mesolimbico: ruolo dell'acetaldeide
… the firing of Ventral Tegmental Area (VTA) mesolimbic dopaminergic neurones (2,3). Moreover, recent data show that ACD blockade by sequestration with D-penicillamine or by alcohol dehydrogenase competitive inhibition with 4-methylpyrazolean prevent various electrophysiological and behavioral …
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The development and use of cutting edge next generation sequencing methodologies to study RNA viruses
… involved in SARS-CoV-2 or ZIKV infection in the mesolimbic pathway, using both snRNA-Seq and PAC-Seq. Our results suggest that opioid use may exacerbate symptoms of these infections by up-regulating inflammation and down-regulating anti-viral pathways in this brain region.
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Assessment of Ethanol and Nicotine Interactions in the Rat Model: Pharmacotherapeutics, Adolescence, and the Mesolimbic System
Alcohol use disorder (AUD) and nicotine dependence often result in serious health problems and are top contributors to preventable deaths worldwide. Co-addiction to alcohol and nicotine is the most common form of polysubstance abuse. Epidemiological studies indicate that more than 80% of …
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Neural Mechanisms of Homeostatic Need and Reward
… hypothalamic control of energy homeostasis and mesolimbic processing of motivation, as well as their roles in the pathogenesis of obesity and addiction, respectively. The first study aims to elucidate the mechanism of how the feeding center develops resistance to leptin, a satiety hormone, and …