Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 28 for “"Mesenteric lymph nodes"”.
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A comprehensive study of Salmonella infections and microbial analysis of probiotics on beef cattle
… beef cattle alongside Salmonella populations of mesenteric lymphatic tissues. Treatment diets fed in this study included a probiotic mixture alone (DFM), inclusion of Tylosin (TYL), a combination of including both (DFM+TYL), and a control group diet that did not include any supplements (CON). …
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Η ΕΠΙΔΡΑΣΗ ΤΗΣ ΑΣΙΤΙΑΣ, ΠΡΩΤΕΙΝΙΚΗΣ ΔΥΣΘΡΕΨΙΑΣ, ΚΥΤΤΑΡΟΣΤΑΤΙΚΩΝ ΚΑΙ ΑΝΤΙΒΙΟΤΙΚΩΝ, ΣΤΗΝ ΑΚΕΡΑΙΟΤΗΤΑ ΤΟΥ ΒΛΕΝΝΟΓΟΝΙΟΥ ΕΝΤΕΡΙΚΟΥ ΦΡΑΓΜΟΥ. (ΠΕΙΡΑΜΑΤΙΚΗ ΜΕΛΕΤΗ)
… TRANSLOCATION FROM THE INTESTINAL LUMEN TO MESENTERIC LYMPH NODES, LIVER, SPLEEN, KIDNEY AND LUNGS, BY CULTURING TISSUES FROM THE ABOVE ORGANS AFTER SACRIFICE. THE PERIOD OF STUDY WAS 24-72 H, AFTERTREATMENT. THE TERMINAL ILEUM OF EACH EXPERIMENTAL ANIMAL WAS HISTOLOGICALLY EXAMINED. IN …
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Pathological Changes and Immunity Associated With Experimental Eimeria Vermiformis Infections in the Mouse (Mus Musculus)
… studied in the small intestine, cecum, colon, mesenteric lymph nodes, liver, spleen and kidney. Surface changes in ileum were studied with the scanning electron microscope (SEM). Immunity to E. vermiformis was determined 30 and 105 DAI. Cross-immunity to E. ferrisi was also studied. An …
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Finding Typhoid Mary: Identifying Latent Carriers of Salmonella enterica serovar Typhimurium
… aceA expression could be detected in cattle lymph node samples. Supra-mammary lymph nodes from 40 dairy cattle and mesenteric lymph nodes from 100 culled cattle were sampled and submitted for culture and qPCR. None of the supra-mammary lymph nodes were positive for Salmonella via culture or …
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Phenotypic and Functional Analysis of Regulatory T Cells during Heligmosomoides polygyrus infection
… and chronic infection from two different gut lymphoid organs, the Peyers patches and mesenteric lymph nodes. Unexpectedly, we found Tregs isolated from infected animals to be equally or less suppressive compared to those from naïve controls. However, we found no difference in the expression of …
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MAdCAM-1 expression and function in human liver
… is a tissue–specific protein that promotes α4β7+ lymphocyte recruitment on gut mucosal endothelium, playing an important role in the development of inflammatory bowel disease (IBD). Recent studies have reported its expression in liver diseases such as primary sclerosing cholangitis (PSC) and …
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Listeria monocytogenes as a Biologic Vaccine Vector Against Feline Immunodeficiency Virus
… These cats maintained normal CD4:CD8 ratios in mesenteric lymph nodes while control cats had inverted ratios. While single, low-dose immunization with LMgag/pND14-Lc-env did not prevent FIV infection; it did reduce viral loads and enabled immunized cats to control viral replication. The second …
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Novel Immunotherapies and Immunoregulation in a Chronic Inflammatory Disease of the Central Nervous System
… with an expansion of regulatory T cells in mesenteric lymph nodes and spleen followed by an increased production of IL-4, IL-10 and TGF-beta. We further demonstrated the powerful therapeutic potential of these bacteria in diseased animals when treating with a combination of these probiotic …
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Exploring the Role of PKD Enzymes in the Innate and Adaptive cells of the Mammalian Immune System
… for normal peripheral CD4+ and CD8+ cytotoxic T lymphocyte function in vivo. PKD enzymes are known to be involved in adaptive immunity but it is not known if this is true for PKD in cells of the myeloid lineage, including dendritic cells (DCs) and macrophages or in myeloid malignancies such as …
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Characterizing Host Protective Immune Responses to the Parasitic Worm Heligmosomoides polygyrus
… during acute and chronic infections. The spleen, mesenteric lymph nodes and Peyer’s patches (PP) had increased eosinophilia, with resident and recruited eosinophil surface markers. In addition, eosinophils accumulated around the protozoan parasite Toxoplasma gondii indicating that intestinal …
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Molecular mechanisms of porcine circovirus 2 replication and pathogenesis
… antibodies, and lower amounts of PCV2 antigen in mesenteric lymph nodes suggested attenuation of muPCV2. However, there was no significant difference in histological or gross lesions in tissues between PCV2- and muPCV2-inoculated groups. The role of ORF3 in attenuation needs to be further …
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Regulation of Autoimmunity and Inflammation by microRNAs and Environmental Factors
… By studying the apoptosis response of NOD lymphocytes (which activates similar cell-cycle checkpoints and apoptosis pathways as during thymocyte maturation) we showed differential expression of the miRNA-34a/b/c gene family, miR-125 and miR-155 in the DNA damage response between NOD and …
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Intestinal Handling of Food Grade Titanium Dioxide
… in the patch. Thus, further work should consider mesenteric lymph nodes as a potential target in such situations. Finally, I show that fgTiO2 does not alter subepithelial dome expression of PD-L1 whether in the presence or absence of Salmonella. Overall, I conclude that ingested fgTiO2 selectively …
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Trichuris Muris Whey Acidic Protein Induces Type 2 Protective Immunity Against Whipworm
… isolated from the vaccine-draining inguinal lymph nodes, parasite-draining mesenteric lymph nodes, and spleen in mice vaccinated with either r<em>Tm</em>-WAP49 or r<em>Tm</em>-WAP-F8+<em>Na</em>-GST-1. The humoral immune correlates included a high antigen-specific ratio of IgG1 to IgG2a, …
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Salmonella Suppress Innate Immunity by Targeting Mast Cells
… and exhibited limited colonization of the mesenteric lymph nodes. Administration of SptP to sites of Escherichia coli infection markedly enhanced its virulence. Thus, SptP-mediated inactivation of local MCs is a powerful mechanism utilized by <italic>S.</italic> Typhimurium to impede early …
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Lymphocyte subset variability between human lymphoid tissues
Most adaptive immune lymphocytes are in the lymphoid tissues. However, studies of human lymphocytes to date have primarily investigated cells from the blood, and lymphoid tissues remain poorly studied. This thesis explores the hypothesis that there is local variation of B cell subsets between the …
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Phenotype and function of intestinal CD103+ dendritic cells
… the villous lamina propria and intestinal lymphoid tissue in both mice and humans are thought to play key roles in this process. DCs at these sites constantly sample and process both luminal and self-antigens and are key players in presenting these antigens to T cells. Recently, intestinal …
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Investigating the role of the gut microbiota on immune checkpoint inhibitor-mediated colitis
… increased bacterial translocation to mesenteric lymph nodes, indicating that intestinal microbial dysbiosis in this setting led to an impairment in intestinal barrier function. Gained knowledge through patient profiling and pre-clinical mouse models will better our understanding of …
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The Role of Bacterial Amyloids In Regulating Gastrointestinal Homeostasis
… the intestinal lumen into the cecal tissue and mesenteric lymph nodes was limited in C57BL/6 mice as compared to TLR2 knockout mice. In the second phase of our studies, we sought to further investigate the effect that curli fibers exert on gastrointestinal homeostasis through the induction of …
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Molecular Mechanisms and Antigen Receptor Requirements for Lymphocyte Adaptation to Intestinal Tissues
… adaptation upon migrating from the gut-draining mesenteric lymph nodes (mLN) to the intestinal lamina propria and epithelium (IE). We sought to elucidate the transcriptional mechanisms and T cell receptor (TCR) signaling requirements of CD4+ T cell plasticity and adaptation in the intestinal …
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