Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 26 for “"Merck"”.
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Because We Have the Power to Choose: A Critical Analysis of the Rhetorical Strategies Used in Merck's Gardasil Campaign
In June of 2006, Merck gained FDA approval for Gardasil, a human papillomavirus vaccine. Shortly before, Merck also launched a large campaign to advertise the vaccine, which has continued through today. Because of the vast number of women the vaccine has the potential to affect, the product has …
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Because We Have the Power to Choose: A Critical Analysis of the Rhetorical Strategies Used in Merck's Gardasil Campaign
In June of 2006, Merck gained FDA approval for Gardasil, a human papillomavirus vaccine. Shortly before, Merck also launched a large campaign to advertise the vaccine, which has continued through today. Because of the vast number of women the vaccine has the potential to affect, the product has …
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Triazole-linked reduced amide isosteres: An approach for the fragment-based drug discovery of anti-Alzheimer's BACE1 inhibitors and NH-assisted Fürst-Plattner opening of cyclohexene oxides
… digit nanomolar) isopththalamide ligand from Merck. We supplanted one of the amide linkages in order to incorporate our triazole and saw a 1000-fold decrease in potency. We then enlisted Molsoft, L.L.C. to compare our ligand to Merck's in silico to account for this discrepancy. They found that …
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Selective functionalization of azines via phosphonium salts
… molecules through a collaborative effort with Merck. In chapter 3, a pyridine-pyridine coupling reaction is discussed using azinyl phosphonium salts as radical precursors. The reaction functions through a radical-radical coupling mechanism using B2pin2 and 4-cyanopyridine as an …
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Fast, efficient generation of high-quality atomic charges
… to handle virtually all organic compounds in The Merck Index and the NCI Database. The AM1-BCC charge model reproduces ab initio dimer energies of a diverse set of molecules with an average error of 0.9 kcal/mol and experimental relative free energies of solvation of a diverse set of compounds …
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Quantitative HPTLC
… manufacturers for both Rf and peak area with E. Merck and Baker plates having the best overall results. All manufacturers were found to have some plates with obvious visual surface defects that were not suitable for use. The major source of variation for all manufacturers was the plate to plate …
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Carbomagnesium mediated reactions: A versatile tool in organic synthesis.
… provided a short (two-steps) synthesis of the Merck anti-inflammatory drug, Vioxx RTM (231). The reaction was also extended to a direct one-step synthesis of the ene-diyne chromophore (186). Additional research afforded a versatile route from 144 to dienophiles for intramolecular Diels-Alder …
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The Fox Guarding the Henhouse: Coregulation and Consumer Protection in Food Safety, 1946 – 2002
<p>Most citizens, business leaders, and government regulators can agree that inspections of food and consumer goods constitute a valuable and even “essential” task of governments. Nevertheless, these groups frequently disagree on what “inspection” means, who should carry it out, and how they should …
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5'-Deacetoxi-hiptenolideo, α-pirona isolada de Hyptis macrostachys Benth.
… utilizando sílica gel 60 (70-230 mesh-ASTM, Merck) como fase estacionária e como fase móvel, os solventes hexano, diclorometano e acetato de etila, puros ou em misturas binárias, obtendo-se 100 frações que após analise em CCDA foram reunidas. A reunião de fração 48 a 63 foi submetida à …
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Relación de las Variables del Clima Organizacional y la Satisfacción Laboral en la Clínica Good Hope, Lima, Perú, en al Año 2009
… 2009.</p> <p>Methodology</p> <p>An adaptation of Merck, Sharp, & Dohme’s questionnaire was used to measure organizational climate. The instrument measures six dimensions of organizational climate: leader practices, peer collaboration, acknowledgment towards the leader, employee development, work …
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Is it Worth the shot? Ontario Women's Negotiations of Risk, Gender and the Human Papillomavirous(HPV) Vaccine
… analyses frames, based on the parameters of Merck Frosst’s gender-based marketing. This case study of the HPV vaccine highlights how corporations and governments work hand and hand to set public health policy in the neoliberal era of public health. However, these sales/governance strategies …
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Using Commercially Available Hormones to Enhance Swine Reproductive Efficiency in Batch Management Systems
… available hormones (MATRIX® and P.G. 600®; Merck Animal Health, De Sota, KS) in a 5-week batch management system had a positive impact on reproductive efficiency in gilts and sows over the course of 3 parities. Gilts were allocated to an Entry Group (A, B, or D) and then assigned to a …
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Use of Triptorelin Acetate for Inducing Ovulation and Facilitating Fixed Time Artificial Insemination of Sows Weaned on Small-Scale and Niche Market Pig Farms
… (n = 24) P.G. 600® (400 IU eCG and 200 IU hCG, Merck Animal Health, Inc., De Sota, KS) injected intramuscularly at weaning, OvuGel at h 96 and AI at h 120; 3) TRT3: (n = 24) P.G. 600 at weaning, and AI at 0 and 24 h after first detection of estrus; and 4) TRT4: (n = 24) AI at 0 and 24 h after …
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Assessment of co-occurrence of cyanotoxins, toxic metals and anionic surfactants in irrigation water, agricultural soils and food crops
… using Spectrophotometer and Spectro-Quant® Merck Pharo 100 with the photo-metric test kits from Merck, respectively. The levels of Microcystins (MCs), anionic surfactants, and metals were detected and quantified using the ELISA method, anionic surfactant portable photometer and inductively …
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The Characterization of Glycosaminoglycans and Metallic Dianions in the Gas Phase
… mechanics and quantum chemical approach. Merck Molecular Force Field 94’ has been utilized to generate candidate structures for higher level B3LYP, PW91PW91, M05-2X and MP2 calculations using the 6-31++G** basis set. This method was used to explore the preferred low energy structures of …
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An Update on Pharmaceutical Strategies for Oral Delivery of Therapeutic Peptides and Proteins
… molecules drugs (12.6 years) estimated using Merck Index. In 2009, US Congress passed the Biologics Price Competition and Innovation Act (BPCIA) which gave new biologics 12 years of guaranteed exclusivity. The most commonly utilized routes for administering TPPs are I.V, I.P or I.M injections, …
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Effect of the timing of OvuGel administration on reproductive performance in gilts sycnhronized for estrus
… of estrus detection and insemination. Matrix® (Merck Animal Health, Summit, NJ) is an orally active progestogen that is used to synchronize estrus in gilts and OvuGel® (JBS United, Sheridan, IN) is a product that has been shown to synchronize ovulation in sows, allowing for a single fixed-time …
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Expression of angiogenic growth factors in laryngeal carcinoma
… Fermentas Life Sciences, York, UK, Calbiochem/Merck, Nottingham, UK) and the expression of 55 angiogenesis-related proteins was determined using a human angiogenesis array (R&D systems). Subsequently the level of six of the 55 angiogenesis-related proteins showing the greatest level of …
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