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Showing 1 to 1 of 1 for “"MenA inhibitors"”.
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Discovery of Natural Product-based Antimycobacterial Agents Effective against Non-replicating Bacilli
… UT-317 is a selective vitamin K2 biosynthesis (MenA) inhibitor that killed replicating and non-replicating Mtb at 2.31 μg/mL (MIC) and 0.85 μg/mL, respectively. A 50-membered library of capuramycin analogs was evaluated in their enzymatic inhibitory activities against translocase I (MraY/MurX) …