Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 15 of 15 for “"Memory decline"”.
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Electrophysiological and Behavioural Markers of Associative Source Memory Decline in Normal Ageing
Memory is the ability to encode and subsequently recall information (Brickman & Stern, 2009) and source memory refers to the ability to recall the source of the information, including all contextual aspects related to an event (Glisky & Kong, 2008; M. Johnson, Hashtroudi, & Lindsay, 1993). The …
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The role of Igf2 methylation and histone ubiquitination in age-related memory decline
Cognitive decline affects nearly 33% of adults over the age of 70 and is a major risk factor for developing dementia and Alzheimer's disease (AD). The hippocampus is one of the major brain regions associated with memory formation, and is one of the first regions impacted in dementia and AD. …
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Advanced clinical MRI for better outcome in epilepsy surgery. Focusing on fMRI and prediction of verbal memory decline.
… of epilepsy surgery, with focus on language and memory functions. Methods: In paper I, 25 patients with drug-resistant epilepsy were retrospectively included in the study for having been referred to high resolution 3T MRI with and without surface coils. The surface coils were placed over the …
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Memory Fidelity in Healthy Ageing and Risk for Cognitive Decline
Memory decline is characteristic of cognitive ageing and it has been suggested that one important factor underpinning the magnitude of age deficits is a reduction in the fidelity or quality of perceptual and mnemonic representations. This thesis examined cognitive and neural underpinnings of …
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Non-proteolytic roles of the ubiquitin-proteasome system in memory formation across the lifespan
Memory formation and decline are driven by complex molecular mechanisms and region-specific changes in the brain. Epigenetic modifications, such as histone monoubiquitination and ubiquitin signaling, have emerged as key players in these processes. While monoubiquitination of histone H2B is a …
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Age Differences in Judging the Frequency of Events.
… recognized by layman and scientist alike that memory functioning decreases to some extent due to aging. Most of the available literature focuses on age changes in memory with respect to storage and retrieval deficits. However, a lack of evidence exists related to some of the more basic …
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Age Related Decline in Memory: Examining the Mediation Effect of Processing, Executive Functioning and Intelligence in Normal Adults
… (i.e., Common Cause, Processing, and Executive Decline Hypotheses) along with other cognitive domains that are sensitive to aging are rare. Moreover, having identified that cognition begins to decline as early as 30 years old, few studies have examined the mechanisms that underlie memory change …
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Aging and Event Segmentation
Episodic memory, our memory for events in our lives, typically becomes less detailed and more prone to error with advancing age. An extensive literature exists investigating age-related memory decline using simple stimuli (e.g., words, pictures), but fewer studies have used naturalistic stimuli …
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The Effect of Age-Related Stereotypes on Memory Self-Efficacy and Memory Task-Performance of Older Adults
… association between stereotypes of age-related memory decline and memory self-efficacy beliefs. It was also hypothesized that this relationship affects performance on measures of memory performance. A measure of age stereotype vulnerability was assessed along with two measures of memory …
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Effects of healthy ageing on the precision of episodic memory
Episodic memory decline is one of the hallmarks of human cognitive ageing, but our understanding of the neurocognitive mechanisms underlying this decline remains limited. In particular, it is unclear whether healthy ageing differentially affects distinct components of episodic memory retrieval; …
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ANALYSIS OF ADULT NEUROGENESIS AND HIPPOCAMPUS-DEPENDENT MEMORY IN MOUSE MODELS FOR AGING, ALZHEIMER’S DISEASE AND CRANIAL IRRADIATION-INDUCED NEUROINFLAMMATION
… every living being differently. Age-associated memory decline can be mild; however, memory can deteriorate quickly with in patients with mild cognitive impairment or a significant brain injury. Investigating therapeutics that support learning and memory mechanisms in subjects at risk for …
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Age related memory loss and the role of the ubiquitin proteasome system
… a vital region of the brain directly involved in memory formation and spatial processing. As individuals age, this area undergoes significant structural changes, including a reduction in volume and modifications in molecular processes. These transformations are an inevitable aspect of the natural …
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Neuroinflammation, Glutamate Regulation and Memory
… neuroinflammation drives changes that indicate a decline in neurotransmitter production and function, and that all these changes recovered over time, despite the continued presence of a neuroinflammatory stimulus. I paralleled these investigations in the hippocampus, a region that degenerates in …
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Predicting the level of cognitive function from standing balance and salivary biomarkers
… the cognitive function of older adults with memory complaints. However, BCAs can be perceived as stressful, have a high ceiling effect, influenced by language barriers and the level of education of patients suffering from memory decline or confusion, and there is a need to explore more …