Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 74 for “"Memory Loss"”.
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Age related memory loss and the role of the ubiquitin proteasome system
… a vital region of the brain directly involved in memory formation and spatial processing. As individuals age, this area undergoes significant structural changes, including a reduction in volume and modifications in molecular processes. These transformations are an inevitable aspect of the natural …
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Kinetic modeling of amyloid fibrillation and synaptic plasticity as memory loss and formation mechanisms
… and system engineering are applied to explain memory-related neuroscientific phenomena. Amyloid fibrillation and synaptic plasticity have been our focus of research due to their significance. The former is related to the pathology of many neurodegenerative diseases and the later is regarded as …
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Early Bird Caregiver Education: A program to support caregivers of individuals living with early stage dementia or memory loss or other cognitive impairments
… of individuals living with early-stage dementia, memory loss, or other cognitive impairments in providing the highest quality of care possible, while also maintaining their own well-being. The program is intended to be led by an occupational therapy practitioner and aims to provide OTs with an …
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Vanishing
… into Chicanx lives where characters grapple with memory, loss, patriarchal thinking, trauma, love, belonging, heartbreak, self-worth and other wound makers in order to move past survival and into a world where they can thrive.
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The neurocognitive mechanisms underlying dissociative amnesia
Dissociative amnesia refers to the loss of autobiographical memory with a presumed psychological cause. This can involve memory loss for traumatic experiences, such as in PTSD. It can also involve more extensive amnesia for several years, or, in its most extreme form, a fugue state involving total …
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Resilience among Older Adults with Cognitive Impairment and Informal Caregivers
… literature on the experience of late-life memory loss and the experience of caring for persons with memory loss. The current research was guided by incorporation of resilience into the stress process model for assessing personal and caregiver burden associated with mild and more severe …
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The role of the microglial P2Y₆ receptor in ageing, development, and tauopathy
… gene (*P2ry6⁻´⁻*) were found to perform worse in memory tests compared to *P2ry6⁺´⁺* mice, but *P2ry6⁻´⁻* mice were protected from ageing-associated memory loss. Finally, in a chronic model of tauopathy, *P2ry6⁻´⁻* mice were protected from both TAU-induced memory loss and tauopathy. The goal of …
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A renewed vision for Amyloid beta and tau in Alzheimer s disease pathophysiology
… affecting the elderly and characterized by memory loss, personality changes and cognitive dysfunction leading to dementia. I will discuss the main projects in which I participated aimed at understanding the role of the main molecular interactors involved in AD pathogenesis, i.e. Amyloid-beta …
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Forgetting To Remember : Remembering To Forget: a space for reconciliation and transformation in post-apartheid South Africa
… Commission, but deals with universal themes of memory, loss and forgiveness. The project critically explores reconciliation resulting from the interplay of memory and forgetting within the spatial confines of the memorial. It explores the functional aspects of both processes expanding on the …
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Qualidade de vida e memória: um estudo na terceira idade
… Increasingly. They Make They have some sort of memory loss. The present work aims to discuss the quality of life of respect and memory in the Middle Third. For IT, it was Realized hum bibliographic Survey on Ageing, as Several faces of old age, quality of life in old age, memory and how its …
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Medical data mining : improving information accessibility using online patient drug reviews
… of alarming disorders, including depression, memory loss, and heart failure. We also develop an initial language model for speech recognition in the medical domain, with transcribed data on sample patient comments collected with Amazon Mechanical Turk. Our findings show that patient-reported …
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Assessing the Effects of Momentary Priming On Memory Retention During An Interference Task
A memory aid, that used brief (33ms) presentations of previously learned information (target words), was assessed on its ability to reinforce memory for target words while the subject was performing an interference task. The interference task required subjects to learn new words and thus interfered …
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Strategy Uses and Study Time: Relationship with Memory Performance in Older Adults
… to foster a greater understanding of age-related memory loss as it pertains to the aging workforce's ability to remain productive and effective in a time of complex change, and to recommend some adjustments that can be made to compensate for these memory declines. The specific intent of this …
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The dynamics of enzymatic switch cascades
… number parameters, and observe the dynamical memory-gain and memory-loss as well as decay in mutual information in quadruple-linked switch systems.
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Experimental and Computational Investigation of Tacrine-Based Inhibitors of Acetylcholinesterase
… AChE has proven an effective treatment for the memory loss exhibited by early stage Alzheimer's disease (AD) patients; four AChE inhibitors (AChEI) have been approved by the FDA for this purpose. The first AChEI approved for the palliative treatment of AD-related memory loss was …
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Veterans of the 1st Persian Gulf War: A Study of Medically Unexplained Symptom Models
… headache, sleep disturbance, low mood, and memory loss. These symptoms were similar to those experienced by individuals with Medically Unexplained Illnesses such as Chronic Fatigue Syndrome, Fibromyalgia, Irritable Bowel Syndrome, Multiple Chemical Sensitivity, and Somatoform Disorders. …
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Targeting Kremen1 Downregulation with RVG-9R/siRNA Complexes in the Triple-Transgenic Mouse Model of Alzheimer’s Disease
… disease characterized by cognitive decline and memory loss. Memory loss observed in AD results from the loss of neurons and synapses which may be caused by the disruption of the canonical Wnt signaling pathway by Dickkopf-1 (Dkk-1). Under normal conditions, the canonical Wnt signaling pathway is …
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Management for Program Sustainability Amidst Rapid Volunteer Turnover
… their missions. Creating a strong institutional memory for both tacit and explicit knowledge and properly managing volunteers are two critical elements in creating the capacity needed to maintain a high-quality program. This thesis analyzes the case of a youth center in Macedonia that is …
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Proteomic-based Signature of Brain-related Proteins as Novel Candidate Biomarkers for Alzheimer’s Disease Diagnosis
… of dementia characterized by the progressive memory loss and cognitive decline, with typical age of onset after 65 years. The main disease hallmarks include extracellular amyloid beta deposits and intracellular neurofibrillary tangles. Brain pathology is reflected in cerebrospinal fluid (CSF) …
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A bright idea? : the promise and peril of a memory drug
… have shown a marked improvement in learning and memory. They are able to master elaborate mazes in half the time of their all-natural counterparts. Wurtman theorizes that the memory loss and dementia associated with Alzheimer's disease is caused not by amyloid plaques and tangles but by a gradual …
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