Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Membrane scaffold protein"”.
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Multidimensional Solid-State NMR Studies of Membrane Proteins
… to study the structure and dynamics of membrane proteins by using uniformly or extensively isotopically labeled samples. In this work, we first optimized the performance of shaped pulses in magic-angle spinning solid-state NMR experiments by characterizing their frequency profiles and …
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Mechanism of anaesthetic activation, combination and antagonism
… receptor reconstitution systems such as membrane-scaffold protein (MSP)-, saposin-, and SMALP nanodiscs. Antibody fragments have been used in the past to support particle alignment and distribution in cryo-EM specimen. On the example of several cryo-EM structures, I will discuss the …
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Omics approach towards understanding the function of bioactive lipids in osteosarcoma
… approach towards identifying specific membrane proteins and lipids that are differentially expressed in normal osteoblasts, non-metastatic and metastatic osteosarcoma. As described in chapter 2, a high throughput peptide fingerprinting enabled us to identify various membrane proteins …
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Incorporation and analysis of bilayer constituents in nanodiscs
… a lipid bilayer and two surrounding amphipathic proteins, have been utilized to house and solubilize integral membrane proteins and other molecules with large hydrophobic groups which limit their aqueous solubility. In the experiments described herein, lipids from the Nanodiscs’ bilayer, …