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Showing 1 to 4 of 4 for “"Membrane protein biochemistry"”.
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Σχεδιασμός, έκφραση και δομικές μελέτες τμημάτων του ανθρώπινου νευρωνικού νικοτινικού υποδοχέα ακετυλοχολίνης
Οι νικοτινικοί υποδοχείς ακετυλοχολίνης (nAChRs) ανήκουν στους υποδοχείς Cys-θηλιάς, που διαμεσολαβούν και ρυθμίζουν την ταχεία συναπτική νευροδιαβίβαση. Είναι πενταμερή κανάλια ιόντων που ενεργοποιούνται από προσδέτη και απαρτίζονται από πέντε ομόλογες υπομονάδες, καθεμία εκ των οποίων …
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Conformational Changes In The Extracellular Domain of Glutamate Receptors
<p>The family of membrane protein called glutamate receptors play an important role in the central nervous system in mediating signaling between neurons. Glutamate receptors are involved in the elaborate game that nerve cells play with each other in order to control movement, memory, and …
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Bioenergetic coupling in P-glycoprotein: determining the relative position, topography and role of transmembrane helices six and twelve
Multidrug efflux pump P-glycoprotein (P-gp) has been the subject of significant research interest since the discovery of the protein in multi-drug resistant cancer cells 40 years ago. Overexpression of P-gp can confer resistance to a broad range of structurally and functionally distinct drugs. The …
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Bioenergetic coupling in P-glycoprotein: determining the relative position, topography and role of transmembrane helices six and twelve
Multidrug efflux pump P-glycoprotein (P-gp) has been the subject of significant research interest since the discovery of the protein in multi-drug resistant cancer cells 40 years ago. Overexpression of P-gp can confer resistance to a broad range of structurally and functionally distinct drugs. The …