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Showing 1 to 1 of 1 for “"Membrane pKa shift"”.
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Novel In-Vitro Approaches to Investigate Membrane Partitioning and pH-Dependent Passive Permeation of Small Molecule Drugs
… of drug molecules through biological membranes is a fundamentally important process that involves the partitioning of molecules into the lipid bilayer membrane and passive permeation across the membrane. The majority of the drug molecules are either weak bases or acids. For these …